Iron Administration Overcomes Resistance to Erastin-Mediated Ferroptosis in Ovarian Cancer Cells
Articolo
Data di Pubblicazione:
2022
Abstract:
Developing novel therapeutic approaches to defeat chemoresistance is the major goal of ovarian cancer research. Induction of ferroptosis has shown promising antitumor effects in ovarian cancer cells, but the existence of still undefined genetic and metabolic determinants of susceptibility has so far limited the application of ferroptosis inducers in vivo.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
chemoresistance; erastin; ferroptosis; iron; mitochondrial dysfunction; ovarian cancer
Elenco autori:
Battaglia, Anna Martina; Sacco, Alessandro; Perrotta, Ida Daniela; Faniello, Maria Concetta; Scalise, Mariangela; Torella, Daniele; Levi, Sonia; Costanzo, Francesco; Biamonte, Flavia
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