Acral Persistent Papular Mucinosis: A New Entity

Dermal mucinoses are a heterogeneous group of diseases in which an abnormal deposition of mucin occurs in the dermis.1 They are distinguished from the follicular mucinoses in which mucin accumulates within the hair follicles. In dermal mucinoses, either a diffuse infiltration or a focal deposit of mucin may occur. In the latter, papules are the usual clinical presentation. The papular mucinoses (PM), however, are far from a homogeneous grouping of disorders. A variety of clinical presentations have been described both with and without accompanying extracutaneous manifestations.We describe two patients with a persistent progressive eruption of multiple asymptomatic papules that proved to be due to a mucin deposit in the upper reticular dermis.