Bosentan blocks the antiangiogenic effects of sera from systemic sclerosis patients: an in vitro study
Articolo
Data di Pubblicazione:
2015
Citazione:
Bosentan blocks the antiangiogenic effects of sera from systemic sclerosis patients: an in vitro study / Romano, Eloisa; BELLANDO RANDONE, Silvia; Manetti, Mirko; Bruni, Cosimo; Lepri, Gemma; MATUCCI CERINIC, Marco; Guiducci, Serena. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 0392-856X. - 33 Suppl 91:(2015), pp. 148-152.
Abstract:
In systemic sclerosis (SSc), clinical evidence has shown that Bosentan may foster the regeneration of the peripheral microcirculatory network. The aim of this study was to verify in vitro the influence of Bosentan on the angiogenic performance of dermal microvascular endothelial cells (MVECs) and its possible capacity to counteract the antiangiogenic effects of SSc sera.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Systemic sclerosis; endothelial cells; angiogenesis; endothelin-1; chemoinvasion; cell proliferation
Elenco autori:
Romano, Eloisa; BELLANDO RANDONE, Silvia; Manetti, Mirko; Bruni, Cosimo; Lepri, Gemma; MATUCCI CERINIC, Marco; Guiducci, Serena
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