fMRI in Psychiatric Disorders

Functional neuroimaging has become an important tool for clinical research, with the potentiality to provide information on psychiatric disease pathology and treatment response. We review functional magnetic resonance imaging (fMRI) research findings for five psychiatric disorders: schizophrenia, major depressive disorder, bipolar disorder, obsessive-compulsive disorder, and posttraumatic stress disorder. Brain functional abnormalities and possible underlying mechanisms for disease symptoms are discussed, with a focus on future clinical implications for fMRI in psychiatric disease.