EARLY IMPLANT INSERTED IN A RECONSTRUCTED SITE WITH XENOGRAFT, HYALURONIC ACID, AND POLYNUCLEOTIDES IN NON-SYNDROMIC AGENESIS: HISTOMORPHOMETRY AND FOLLOW-UP

The present clinical case aims to investigate how a mixture of polynucleotides and hyaluronic acid in gel form, combined with bovine-derived heterologous material, can expedite the process of bone neoformation suitable for implant placement. In this case, the biomaterials are covered with a resorbable membrane and stabilization pins to protect the grafted material. A patient with severe, non-syndromic multiple dental agenesis is described. After five months, implant placement was performed. Following a core drilling biopsy at the implant insertion site, histomorphometric investigations were conducted to assess the maturation status of the regenerated bone site. After 6 months of implant healing, prosthetic procedures were performed, followed by a subsequent radiographic follow-up. Upon return, the regenerated bone appeared well vascularized before implant placement and provided adequate primary stability.