Multimodal imaging of amelanotic choroidal melanoma

Amelanotic choroidal melanoma (ACM) is an extremely rare malignant tumor affecting the uvea. Because of the complex structure characterizing this kind of lesions, its morphologic features are partially understood, especially if looking to its vascular network. In this paper, we described in details the multimodal imaging features of ACM. Moreover, we disclosed new insights about different orders of blood vessels characterizing this tumor. Despite the entire vascular network is partially detectable by conventional dye-based angiography, it was reconstructed in its entirety by means of optical coherence tomography angiography. In conclusion, multimodal imaging represents a feasible and useful set of tools, able to describe in deep ACM features and its vascular network organization, and to provide clinically relevant information for ACM management.