BLOOD

Rivista

Codice:

E023052

ISSN:

0006-4971

Dati Generali

Pubblicazioni (559)

A -25G>A hepcidin promoter mutation in a Portuguese patient with juvenile hemochromatosis, Turner syndrome and severe lymphopenia

Articolo

A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

Articolo

A Mechanistic Role For Mir-126, a Hematopoietic Stem Cell Microrna, In Acute Leukemias

Abstract

A Phase III Study of Enoxaparin Versus Low-Dose Warfarin Versus Aspirin as Thromboprophylaxis for Patients with Newly Diagnosed Multiple Myeloma Treated up-Front with Thalidomide-Containing Regimens

Abstract

A Recent Update of Three Consecutive Prospective Trials with High-Dose Therapy and Autograft, without or with Rituximab, as Primary Treatment for Advanced-Stage Follicular Lymphoma (FL) Shows a Sizeable Group of Patients Surviving in Continuous Complete Remission up to 16 Years After the End of Treatment: Should We Still Consider FL An Incurable Disease ?

Articolo

A Six-Month Regimen of Oral Clarithromycin Is a Feasible and Active Therapy for Patients with Relapsed/Refractory Marginal Zone B-Cell Lymphoma of MALT-Type

Abstract

A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation

Articolo

A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes (TEMs), blood “resident” monocytes and embryonic macrophages suggests common functions and developmental relationships

Articolo

A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR

Articolo

A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia.

Abstract

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice

Articolo

A new G51C mutation in the IRE of L-ferritin in hyperferritinemia cataract syndrome decreases the binding affinity of the mutant IRE to IRP.

Abstract

A new chromogranin A-dependent angiogenic switch activated by thrombin

Articolo

A new hereditary persistence of fetal hemoglobin deletion has the breakpoint within the 3' beta-globin gene enhancer

Articolo

A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL.

Articolo

A novel Rag2(-/-)gamma(-/-)(c)-xenograft model of human CLL

Articolo

A novel function of FOXP3 in humans: intrinsic regulation of conventional T cells

Articolo

A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA

Articolo

A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD

Articolo

A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT.

Abstract

A proportion of patients with lymphoma may harbor mutations of the perforin gene

Articolo

A randomized trial of bone marrow (BM) versus peripheral blood (PB) allogeneic hemopoietic stem cell transplants (HSCT) in patients with myeloproliferative disorders.

Articolo

A randomized trial of rabbit anti-thymocyte globulin, given on day+7 after alternative donor transplants.

Articolo

A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice

Articolo

A second CD19 CAR T-cell infusion: Yes or no?

Articolo

A strategy for introducing and targeting antigen in activated dendritic cells for simultaneous stimulation of CD4 and CD8 cells.

Contributo in Atti di convegno

A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: a risk factor analysis of outcomes for patients in remission at transplantation

Articolo

A valine deletion of ferroportin 1 is a common mutation in hemochromatosis type 4

Articolo

ACQUISITION OF INTACT ALLOGENEIC HUMAN LEUKOCYTE ANTIGEN MOLECULES BY HUMAN DENDRITIC CELLS

Articolo

ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency

Articolo

Abnormal VWF modifies megakaryocytopoiesis: studies of platelets and megakaryocyte cultures from patients with von Willebrand disease type 2B

Articolo

Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation.

Abstract

Acalabrutinib-obinutuzumab improves survival vs chemoimmunotherapy in treatment-naive CLL in the 6-year follow-up of ELEVATE-TN

Articolo

Acquisition of intact allogeneic HLA molecules by human dendritic cells.

Abstract

Activation of alpha-diacylglycerol kinase is critical for the mitogenic properties of anaplastic lymphoma kinase

Articolo

Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells

Articolo

Activity of rituximab in extranodal marginal zone lymphomas (MALT-type).

Abstract

Acute Myeloid Leukemia Relapses after Allogenenic HSCT Display a Distinctive Immune-Related Signature, with Frequent and Functionally Relevant Alterations in HLA Class II Antigen Presentation and T Cell Costimulation

Abstract

Adhesion, transendothelial migration, and reverse transmigration of in vitro cultured dendritic cells

Articolo

Adoptive T-cell therapy for B-cell acute lymphoblastic leukemia: preclinical studies

Articolo

Allogeneic Bone Marrow Transplantation From Unrelated Donors in Multiple Myeloma: A Study from the Italian Bone Marrow Transplantation Donor Registry

Abstract

Allogeneic Hematopoietic Stem Cell Transplantation For Severe Neuromyelitis Optica

Abstract

Allogeneic Stem Cell Transplantation (Allo-SCT) Following a Reduced-Intensity Conditioning (RIC) Regimen in Relapsed Peripheral T-Cell Lymphomas (PTCL): Results at 4 Year of Median Follow-up

Abstract

Allogeneic Stem Cell Transplantation (Allo-SCT) after Treatment with Programmed Cell Death-1 (PD-1) Checkpoint Inhibitors for Relapsed/Refractory Classic Hodgkin Lymphoma (R/R cHL) Is Associated with an Unprecedented Low Relapse Rate

Abstract

Allogeneic hematopoietic stem cell transplantation in thalassemia major: Results of a reduced-toxicity conditioning regimen based on the use of treosulfan

Articolo

Allogeneic transplantation improves the overall and progression-free survival of Hodgkin lymphoma patients relapsing after autologous transplantation: a retrospective study based on the time of HLA typing and donor availability

Articolo

Allografting for patients with advanced hematological malignancies: Non-myeloablative conditioning followed by the reinfusion of lymphocytes engineered with HSV thymidine kinase gene.

Abstract

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

Articolo

Altered T-cell receptor +CD28- mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease

Articolo

Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients

Articolo

An Accelerated CD8+, but Not CD4+, T -Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT

Abstract

An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia

Abstract

Analysis of ferritins in lymphoblastoid cell lines and in the lens of subjects with hereditary hyperferritinemia-cataract syndrome

Articolo

Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

Articolo

Anemia and iron overload due to compound heterozygosity for novel ceruloplasmin mutations

Articolo

Angiogenesis Associated with Alterations of the Bone Marrow Microenvironment Predicts Multiple Myeloma Progression to Symptomatic Disease in Mice and Humans

Abstract

Anti-CD20 monoclonal antibody (Rituximab) in gastric extranodal marginal zone (MALT) non-Hodgkin's lymphoma (NHL) patients: Clinical and biological results (Phase II study).

Abstract

Anti-CD3{epsilon} mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: therapeutic implications

Articolo

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: Evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

Articolo

Anti-leukemia potential of interleukin-2 activated natural killer cells after bone marrow transplantation for chronic myelogenous leukemia

Articolo

Antifungal Prophylaxis with Posaconazole in Allogeneic Hematopoietic Stem Cell Transplantation Using Sirolimus for Prevention of Graft-Versus-Host Disease

Abstract

Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation

Articolo

Array-CGH Identifies Both Common and Subtype-Specific Genomic Aberrations in Marginal Zone Lymphomas

Abstract

Array-CGH Identifies Regions, Including the FOXP1 Locus, Associated with Different Clinical Outcome in Diffuse Large B-Cell Lymphomas (DLBCL) Treated with R-CHOP

Abstract

Assessment of CD37 B-cell antigen and cell of origin significantly improves risk prediction in diffuse large B-cell lymphoma

Articolo

Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans

Abstract

Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life

Articolo

Autologous Hematopotoietic Stem Cell Transplantation in Multiple Sclerosis with An Intermediate Intensity Conditioning Regimen: The Italian Multi-Centre Experience

Abstract

Autologous and Allogeneic Stem Cell Transplantation for Richter's Transformation: A Retrospective Analysis From the Chronic Leukaemia Working Party and Lymphoma Working Party of the EBMT

Articolo

BLIMP1 Is Commonly Inactivated In Anaplastic Large T-Cell Lymphomas (ALCL)

Abstract

Backtracking Leukemia Clonal Evolution from PostTransplantation Relapse to Initial Diagnosis to Identify Founder Mutations and Mechanisms of Immune Evasion

Abstract

Basiliximab (Simulect (R)) for the treatment of steroid-resistant graft-versus-host-disease (GvHD) after nonmyeldablative allogeneic hematopoietic stem cell transplantation (HSCT).

Articolo

Bendamustine in Combination with Gemcitabine and Vinorelbine (BEGEV) Is an Effective Regimen for Heavily Pretreated, Relapsed/Refractory Hodgkin Lymphoma Patients: A Multicenter, Retrospective Real-World Study

Abstract

Benefit of rituximab addition to high-dose programs with autograft for B-cell lymphoma: A multicenter GITIL survey on 957 patients.

Articolo

Beta-arrestin 2 is required for the induction and strengthening of integrin-mediated leukocyte adhesion during CXCR2-driven extravasation

Articolo

Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis

Articolo

Bone marrow as an alternative site for islet transplantation

Articolo

Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets

Articolo

Bugs and marginal zone lymphoma of the ocular adnexae: is the future already here?

Articolo

Busulfan (Bu) Plus Cyclophosphamide (Cy) Versus TBI Plus Cy Conditioning for Allogeneic Stem Cell Transplantation (alloSCT) From Matched Unrelated Donors (MUD) In Adult Patients with AML in First Relapse: A Survey From the Acute Leukemia Working Party of EBMT

Abstract

C-Myc- Dependent Stabilization of Hif-1alpha in MM: Therapeutic Implications

Abstract

CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5(+) B lymphocytes

Articolo

CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program Study

Articolo

CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma

Articolo

CLL and COVID-19: light at the end of the tunnel?

Articolo

CMV reactivation in patients undergoing reduced-intensity allogeneic stem cell transplantation: Association with graft-versus-host disease and transplant related mortality.

Articolo

COVID-19 prophylaxis: half-full or half-empty glass?

Articolo

CS1 Promotes Multiple Myeloma Cell Adhesion, Clonogenic Growth, and Tumorigenicity Via C-Maf-Mediated Interactions with Bone Marrow Stromal Cells (BMSC)

Abstract

CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf-mediated interactions with bone marrow stromal cells

Articolo

CS1, a new surface target on multiple myeloma (MM) cells, protects myeloma cells from apoptosis via-regulation of ERKI/2, AKT and STAT3 signaling cascades

Abstract

Calreticulin Mutation Is Associated with Milder Disease in Patients with Post Essential Thrombocythemia Myelofibrosis (PET-MF) Compared with JAK2V617F Mutation: A Study from the AGIMM Group

Abstract

Calreticulin Mutation Is Associated with Milder Disease in Patients with Post Essential Thrombocythemia Myelofibrosis (PET-MF) Compared with JAK2V617F Mutation: A Study from the AGIMM Group

Articolo

Characteristics and expression of binding sites specific for ferritin H-chain on human cell lines.

Articolo

Chemoattractants MDC and TARC are secreted by malignant B-cell precursors following CD40 ligation and support the migration of leukemia-specific T cells

Articolo

Chemotactic activity of recombinant human granulocyte colony stimulating factor

Articolo

Chlamydia psittaci-eradicating antibiotic therapy as a potential therapeutic strategy against marginal zone B-cell lymphoma of the ocular adnexa

Abstract

Cholesterol: a putative oncogenic driver for DLBCL

Articolo

Chronic lymphocytic leukemia management in Italy during the COVID-19 pandemic: A Campus CLL report

Articolo

Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis

Articolo

Clearance of circulating activated platelets in polycythemia vera and essential thrombocythemia

Articolo

Clinical Relevance of the Dose of Cytarabine In the Treatment of Primary CNS Lymphomas with Methotrexate-Cytarabine Chemotherapy Combination.

Abstract

Clinical activity of rituximab in extranodal marginal zone B-cell lymphoma of MALT type

Articolo

Clinical presentation, management and prognosis of angiotropic lymphoma in western countries: The IELSG experience on 37 HIV-negative cases.

Abstract

Clonal B-cell lymphocytosis: a new member?

Articolo

Clonal analyses of retroviral vector integrations in ADA-SCID patients treated with stem cell gene therapy

Abstract

Co-transplantation of ex-vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem cell transplantation

Articolo

Combining Whole Exome Sequencing and Rnaseq to Provide a Comprehensive Landscape of the Mechanisms of Post-Transplantation Leukemia Relapse

Abstract

Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues

Articolo

Comprehensive genome-wide profile of regional gains and losses in multiple myeloma using array-CGH: The 1q21 amplification and potential role of the BCL-9 gene in multiple myeloma pathogenesis

Abstract

Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease

Articolo

Constitutive activation of STATs upon in vivo human immunodeficiency virus infection

Articolo

Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy

Articolo

Correcting b-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity

Articolo

Cyclin D3 immunoreactivity (IR) is an independent predictor of survival and drives the correct assessment of p27(KIP1) IR prognostic role in primary gastric lymphomas (PGL).

Abstract

Cytogenetic complexity in chronic lymphocytic leukemia: Definitions, associations, and clinical impact

Articolo

Cytotoxicity Is Not Required for the Anti-Leukemia Efficacy of Human H-Y-Specitic CD4+T Lymphocytes In Vivo.

Abstract

DEFECTIVE TARGETING OF HEMOJUVELIN TO PLASMA MEMBRANE IS A COMMON PATHOGENETIC MECHANISM IN JUVENILE HEMOCHROMATOSIS

Articolo

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

Articolo

DYSFUNCTIONAL CYTOKINE PRODUCTION BY HOST-REACTIVE T-CELL - CLONES ISOLATED FROM A CHIMERIC SEVERE COMBINED IMMUNODEFICIENCY PATIENT TRANSPLANTED WITH HAPLOIDENTICAL BONE-MARROW

Articolo

Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia

Articolo

Delineation of specific beta-thalassemia mutations in high-risk areas of Italy: a prerequisite for prenatal diagnosis.

Articolo

Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma

Articolo

Detailed safety profile of acalabrutinib vs ibrutinib in previously treated chronic lymphocytic leukemia in the ELEVATE-RR trial

Articolo

Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25(+)CD4(+) Tr cells

Articolo

Differentiation of chronic lymphocytic leukaemia cells: correlation between the synthesis and secretion of immunoglobulin and the ultrastructure of the malignant cells

Articolo

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

Articolo

Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma

Articolo

Distinctive Patterns of Intraclonal Diversification In IGHV1-2*04 Immunoglobulin Receptors of Patients with Splenic Marginal Zone Lymphoma: A of Ongoing Interactions with Antigen?

Abstract

Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia.

Articolo

Droplet Digital PCR for DNMT3A and IDH1/2 Mutations to Improve Early Diagnosis of Acute Myeloid Leukemia Relapse after Allogeneic HSCT

Abstract

Dual Transgenesis of T Cells with a Novel CD44v6-Specific Chimeric Antigen Receptor and a Suicide Gene for Safe and Effective Targeting of Chemoresistance in Hematopoietic Tumors

Abstract

EXPRESSION OF CD33, CD38, AND HLA-DR ON CD34+ HUMAN FETAL LIVER PROGENITORS WITH A HIGH PROLIFERATIVE POTENTIAL

Articolo

Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality

Abstract

Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome

Articolo

Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia

Poster

Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Abstract

Effect of HLA-matching on outcome of hematopoietic stem cell transplantation from unrelated donors: A IBMDR-GITMO study

Articolo

Effect of Related and Unrelated Donor Haemopoietic Stem-Cell Transplantation on Outcome In Adults with High Risk Acute Leukemia: An Intention-to-Treat Analysis at a Single Center Institution

Abstract

Effect of acidic and basic isoferritins on in vitro growth of human granulocyte-monocyte progenitors.

Articolo

Effect of age and previous autologous transplant on treatment-related mortality and GVHD in 140 patients treated with reduce-intensity conditioning and allograft for advanced hematological malignancies.

Articolo

Effect of bortezomib on theAutonomic nervous system.

Articolo

Efficacy and safety of dinaciclib vs ofatumumab in patients with relapsed/refractory chronic lymphocytic leukemia

Articolo

Efficacy of fludarabine and cytarabine combination for salvage treatment of refractory/relapsed myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML): Promising results from a single center experience.

Articolo

Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia

Articolo

Endogenous CCL2 (monocyte chemotactic protein-1) modulates human immunodeficiency virus type-1 replication and affects cytoskeleton organization in human monocyte-derived macrophages

Articolo

Epitope-specific typing (EST) for HLA-DPB1 matching: Proof of principle for an innovative approach to unrelated hematopoietic stem cell donor selection.

Articolo

Erdheim-Chester disease: Consensus recommendations for evaluation, diagnosis, and treatment in the molecular era

Articolo

Evidence for the significant role of immunoglobulin light chains in antigen recognition and selection in chronic lymphocytic leukemia

Articolo

Evidence of serum immunoglobulin abnormalities up to 9.8 years before diagnosis of chronic lymphocytic leukemia: a prospective study

Articolo

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects

Articolo

Ex vivo generation of human anti-pre-B leukemia-specific autologous cytolytic T cells

Articolo

Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset 8

Articolo

Exploiting the Gut Microbiota to Boost Immunotherapy and Switch the Trajectory of Multiple Myeloma

Abstract

Expression of apoptotic markers in activated platelets is mediated in part by cathepsin

Abstract

Extranodal non-gastric malt lymphomas: An international survey of 278 cases.

Abstract

FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk.

Articolo

FLK-2/FLT-3 LIGAND REGULATES THE GROWTH OF EARLY MYELOID PROGENITORS ISOLATED FROM HUMAN FETAL LIVER

Articolo

Facing the Rising Tide of Multidrug Resistant Gram-Negative Pathogens in Allogeneic HSCT with Nanosphere's Verigene((R)) System

Abstract

Factors affecting efficacy of HSV-TK-transduced donor peripheral blood lymphocytes after allo-BMT.

Abstract

Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3

Articolo

Ferritin is secreted via 2 distinct nonclassical vesicular pathways

Articolo

Final Results of a Multicenter Phase II Trial Assessing the Activity and Efficacy of Helicobacter Pylori-Eradicating Antibiotic Therapy As Exclusive Treatment for Patients with Stage I-III Diffuse Large B-Cell Lymphoma of the Stomach (the HGL-1 Trial)

Abstract

Final Results of a Multicenter Phase II Trial with Translational Elements to Investigate the Possible Infective Causes of Ocular Adnexal Marginal Zone B-Cell Lymphoma (OAMZL) with Particular Reference to Chlamydia Species and the Efficacy of Doxycycline As First-Line Lymphoma Treatment (the IELSG#27 TRIAL)

Abstract

Final analysis of the RESONATE-2 study: up to 10 years of follow-up of first-line ibrutinib treatment for CLL/SLL

Articolo

Fixed-duration ibrutinib plus venetoclax for first-line treatment of CLL: primary analysis of the CAPTIVATE FD cohort

Articolo

Flotetuzumab as Salvage Immunotherapy for Refractory Acute Myeloid Leukemia

Articolo

From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia

Contributo in Atti di convegno

Function of HSV-TK suicide gene transduced canine cytotoxic T lymphocytes.

Contributo in Atti di convegno

Functional adenosine diphosphate-activated P2X1del receptor -: Response

Articolo

Furin mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

Articolo

Gastric MALT lymphomas prospective LY03 randomised cooperative trial: Preliminary results of the molecular follow-up.

Abstract

Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model

Articolo

Gene therapy for beta-thalassemia: Preclinical studies on human cells.

Contributo in Atti di convegno

General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLL.

Articolo

Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation

Articolo

Genetic and Phenotypic Attributes of Splenic Marginal Zone Lymphoma

Articolo

Genome Wide-DNA Profiling of Richter's Syndrome-Diffuse Large B-Cell Lymphoma (RS-DLBCL): Differences with De Novo DLBCL and Possible Mechanisms of Transformation from Chronic Lymphocytic Leukemia

Abstract

Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome

Articolo

Genomic Loss of the Mismatched HLA Locus in Leukemia Is a Major Mechanism of in Vivo Escape from T Cell Immunosurveillance Following Haploidentical HSCT

Contributo in Atti di convegno

Genomic and Transcriptional Immunoediting of Acute Myeloid Leukemia in Response to Allogeneic Hematopoietic Stem Cell Transplantation

Abstract

Genomic determinants of response and resistance to pirtobrutinib in relapsed/refractory chronic lymphocytic leukemia

Articolo

Genomic loss of patient-specific HLA in acute myeloid leukemia relapse after well-matched unrelated donor HSCT

Articolo

Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 gene

Articolo

Graft failure after T-cell-depleted human leukocyte antigen identical marrow transplants for Leukemia: I. Analysis of risk factors and results of secondary transplants.

Articolo

Graft failure after T-cell-depleted human leukocyte antigen identical marrow transplants for leukemia: II. In vitro analyses of host effector mechanisms.

Articolo

Graft-versus-lymphoma effect in peripheral T-cell lymphomas (PTCL): Reduced-intensity conditioning followed by allogeneic transplantation gives a better outcome than high-dose chemotherapy followed by autografting.

Articolo

Graft-versus-tumor effect following reduced-intensity allogeneic stem cell transplantation in renal cell cancer. On behalf of the EBMT solid tumours working party.

Articolo

GvHD Kinetics after Haploidentical TK-Cells: In-Vivo HSV-TK Suicide Machinery Is Effective in GvHD Control and Provide a Long-Term Immune-Suppressive Treatment-Free Survival

Abstract

H-ferritin receptors, intracellular H-ferritin and tumor necrosis factor alpha in activated THP-1 myielomonocytic cells.

Abstract

HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment

Articolo

HIV-1 envelope-dependent restriction of CXCR4-using viruses in child but not adult untransformed CD4+ T-lymphocyte lines

Articolo

HLA Loss Leukemia Relapses after Partially-Incompatible Allogeneic HSCT As a Prototypical System to Investigate Natural Killer Cell Dynamics

Abstract

HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders

Articolo

HS1 has a central role in the trafficking and homing of leukemic B cells

Articolo

HSV-TK engineered donor lymphocytes add-backs reduce late mortality and improve survival of high risk acute leukemia after haplo-HSCT: Results of a phase II multicenter trial.

Abstract

HTLV-II down-regulates HIV-1 replication in IL-2-stimulated primary PBMC of coinfected individuals through expression of MIP-1 alpha

Articolo

HUMAN ENDOTHELIAL-CELLS EXPRESS INTEGRIN RECEPTORS ON THE LUMINAL ASPECT OF THEIR MEMBRANE

Articolo

Haploidentical Allogeneic Stem Cell Transplantation in Poor Risk Cytogenetic Acute Myeloide Leukemia: Results in 33 Patients

Abstract

Haploidentical Hematopoietic Stem Cell Transplantation with Treosulfan-Based Conditioning Regimen for Acute Leukemia Relapsing after Initial Allogeneic Transplantation

Abstract

Helicobacter pylori eradication as exclusive treatment for limited-stage gastric diffuse large B-cell lymphoma: results of a multicenter phase 2 trial.

Articolo

Hematopoietic stem cell function in b-thalassemia is impaired and is rescued by targeting the bone marrow niche

Articolo

Hematopoietic stem cell transplantation for Wiskott-Aldrich syndrome: an EBMT Inborn Errors Working Party analysis.

Articolo

Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity: an EBMT IEWP study

Articolo

Hemophilia and nonprogressing human immunodeficiency virus type 1 infection

Articolo

Hemophiliacs with nonprogressive human immunodeficiency virus disease - Response

Articolo

Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12(low/neg) accessory cells with dendritic-cell features

Articolo

Hepcidin is decreased in TFR2-Hemochromatosis

Articolo

Heterozygous missense mutations in the GLRX5 gene cause sideroblastic anemia in a Chinese patient

Articolo

High alloreactive potential of central memory T-lymphocytes expressing a suicide gene for the cure of hematologic malignancies.

Articolo

High remission rate with the FLAG-IDA regimen in myelodysplastic syndromes (MDS) and secondary acute myeloid leukemia (sAML) patients up to 70 years old.

Articolo

High-Sensitivity Hematopoietic Chimerism By qPCR For Relapse Prediction and Specific Identification Of HLA Loss Leukemic Variants

Abstract

High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors

Articolo

High-risk chronic lymphocytic leukemia in the era of pathway inhibitors: Integrating molecular and cellular therapies

Articolo

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL

Articolo

Histopathological EXAMINATION of BONE MARROW Biopsy (BMB) IN Primary Splenic B CELL Lymphomas of Marginal-ZONE ORIGIN (PSMZL). A Reliable Substitute for Spleen Pathology?

Abstract

Hot spots of retroviral integration in human CD34+ hematopoietic cells

Articolo

How I treat ADA deficiency

Articolo

How I treat relapsed childhood acute lymphoblastic leukemia

Articolo

How I treat unexplained refractory iron deficiency anemia

Articolo

Hsv-Tk engineered donor lymphocytes provide early immune reconstitution and control of Gvhd after haplo-identical hemopoietic stem cell transplantation.

Abstract

Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus

Articolo

Human Herpes Virus 6 Infection in 54 Patients after Allogeneic Hematopoietic Stem Cell Transplantation: Clinical Manifestations and Outcome

Abstract

Human Herpes Virus-6 and Clinical Manifestations After Allogeneic Hematopoietic Stem Cell Transplantation

Abstract

Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence

Articolo

Human T-cell leukemia virus type 2 induces survival and proliferation of CD34(+) TF-1 cells through activation of STAT1 and STAT5 by secretion of interferon-gamma and granulocyte macrophage-colony-stimulating factor

Articolo

Human immunodeficiency virus replication induces monocyte chemotactic protein-1 in human macrophages and U937 promonocytic cells

Articolo

Hyperfunctional coagulation factor IX improves the efficacy of gene therapy in hemophilic mice

Articolo

Hypomorhic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype

Articolo

Hypomorphic Rag mutations can cause destructive midline granulomatous disease

Articolo

Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development

Articolo

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia

Articolo

IL-10 and TGF-{beta} induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

Articolo

IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes

Articolo

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors

Articolo

IL-7 receptor expression identifies suicide gene-modified allospecific CD8(+) T cells capable of self-renewal and differentiation into antileukemia effectors

Articolo

Ibrutinib in CLL: benefit for all?

Articolo

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

Articolo

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

Articolo

Identification of alternative forms of a P2X(1) receptor in platelets and megakaryocytic cells.

Abstract

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer

Articolo

Immumoreactivity for cyclin D3 is frequently detectable in high-grade primary gastric lymphomas in the absence of the t(6;14)(p21.1;q32.3).

Abstract

Immune Effector Cell-Associated Hematotoxicity (ICAHT): EHA/EBMT Consensus Grading and Best Practice Recommendations

Articolo

Immune Reconstitution and Immune Correlates of Clinical Outcome in Acute Leukemia Patients Treated with Haploidentical stem cell transplantation

Abstract

Immune Reconstitution and Thymic Function After Reduced Intensity Allogeneic Hematopoietic Cell Transplantation

Poster

Immunity against the transgene product may limit efficacy of HSV-tk-transduced donor peripheral blood lymphocytes after allo-BMT.

Abstract

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL

Articolo

Immunoglobulin Gene Repertoire in Ocular Adnexa Lymphomas (OAL): Hints on the Nature of the Antigenic Stimulation

Abstract

Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation

Articolo

Immunoreactivity for CD10 but not for bcl-6 identifies different risk groups in stage I-II diffuse large B-cell lymphomas of the stomach.

Abstract

Impact of Immune Reconstitution (IR) and Graft-Versus-Host Disease (GvHD) on Clinical Outcomes after Treatment with Donor T Cells Transduced to Express the Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK cells) in Acute Leukemia Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)

Contributo in Atti di convegno

Impaired GvL potential of natural killer cells early reconstituting following haploidentical HSCT.

Articolo

Implementation of An Alternative Donor Option Is Prerequisite for a Good Intention-to-Treat (ITT) In Patients In Need of Allogeneic Transplantation: Analysis of 410 Patients

Abstract

Improved Clinical Outcome of Adult Patients with Ph plus ALL After a Combined Imatinib-Chemotherapy Induction/Consolidation Program Followed by Allogeneic Hematopoietic Stem Cell Transplantation: Results From a Prospective Study of the Northern Italy Leukemia Group

Abstract

Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)

Articolo

In CLL, epigenetics also points to the BCR

Articolo

In vitro activity of SYK and BCR-ABL inhibitors in aggressive lymphomas.

Abstract

In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor

Articolo

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance

Articolo

In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance

Articolo

Incidence of secondary myelodysplastic syndrome/acute leukemia in 1,266 lymphoma patients following high-dose therapy and autograft: A study from GITIL (Gruppo italiano terapie innovative nei linfomi).

Articolo

Incidence, Risk Factors and Clinical Outcome Of Leukemia Relapses Due To Loss Of The Mismatched HLA Haplotype After Partially-Incompatible Hematopoietic Stem Cell Transplantation

Abstract

Incidence, Temporal Trends, and Predictors of Thrombocytopenia Among HIV-Infected Persons Treated with Combined Antiretroviral Therapy (cART)

Abstract

Increased fragmentation of von Willebrand factor, due to abnormal cleavage of the subunit, parallels disease activity in recurrent hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and discloses predisposition in families

Articolo

Increased susceptibility to iron deficiency of Tmprss6-haploinsufficient mice

Articolo

Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus

Articolo

Infusion of Donor Lymphocytes Genetically Engineered to Express the Herpes Simplex Virus Thymidine Kinase (HSV-TK) Suicide Gene after Haploidentical Hematopoietic Stem Cell Transplantation (HSCT): Preliminary Efficacy Data from the Randomized TK008 Study

Abstract

Infusion of HSV-tk genetically-engineered donor lymphocytes restores anti-viral immunity early after allogeneic BMT.

Abstract

Infusions of HSV-TK engineered donor lymphocytes effectively protect patients undergoing haploidentical stem cells trasplantation (HSCT) from infectious mortality

Abstract

Inherited genetic susceptibility to monoclonal B-cell lymphocytosis

Articolo

Inherited perforin and fas mutations in a patient with autoimmune lymphoproliferative syndrome and lymphoma.

Articolo

Integration of Retroviral Vector Induces Minor Changes in the Transcriptional Activity of T Cells from ADA-SCID Patients Treated with Gene Therapy

Articolo

Intensification Of Treosulfan and Fludarabine-Based Conditioning With 4 Gy TBI For Allogeneic Stem Cell Transplantation In Patients With Hematological Malignancies

Abstract

Interaction between Hb Hasharon and alpha-thalassemia: an approach to the problem of the number of human alpha loci

Articolo

Interaction of a rare illegitimate recombination event and poly A addition site -thalassemia.mutation resulting in a severe form of

Articolo

Interleukin-1 blockade in patients with Wiskott-Aldrich syndrome: a retrospective multinational case series

Articolo

Interleukin-10 Anergized Donor T Cell Infusion Improves Immune Reconstitution without Severe Graft-Versus-Host-Disease After Haploidentical Hematopoietic Stem Cell Transplantation

Abstract

Interleukin-6 induces monocyte chemotactic protein-1 in peripheral blood mononuclear cells and in the U937 cell line

Articolo

Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines

Articolo

International consensus statement on diagnosis, evaluation, and research of Richter transformation: the ERIC recommendations

Articolo

Intraocular lymphoma (IOL): Treatment and outcome in HIV-patients.

Abstract

Intrasplenic chemotherapy (ISCT) for hypersplenism in myelofibrosis (MF)

Abstract

Invariant NKT cells contribute to chronic lymphocytic leukemia surveillance and prognosis

Articolo

Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases

Articolo

Isolated bone marrow manifestation of HIV-related Hodgkin Lymphoma.

Abstract

Italian type of deletional hereditary persistence of fetal hemoglobin.

Articolo

KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function

Articolo

KDM6A regulates immune response genes in multiple myeloma

Articolo

Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models

Articolo

Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models (Blood (2011) 1183, 3 (660-669))

Articolo

Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells

Articolo

Lentiviral gene transfer and ex vivo expansion of human primitive stem cells capable of primary, secondary, and tertiary multilineage repopulation in NOD/SCID mice

Articolo

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection.

Articolo

Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo

Articolo

Leukemic Dendritic Cells Expand Central Memory T Lymphocytes From HCT Donors Able to React against the Original Leukemia in Vitro and In Vivo.

Abstract

Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells

Abstract

Leukoencephalopathy and papovavirus infection after treatment with chemotherapy and anti-CD20 monoclonal antibody

Articolo

Ligand-engaged urokinase-type plasminogen activator receptor and activation of the CD11b/CD18 integrin inhibit late events of HIV expression in monocytic cells

Articolo

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.

Articolo

Lipid Nanoparticles Allows Efficient and Harmless Ex Vivo Gene Editing of Human Hematopoietic Cells

Articolo

Long term follow-up in 30 patients receiving HSV-TK transduced donor lymphocytes after allo-BMT.

Articolo

Long-Term Follow-up of Patients Affected by Relapsed Lymphomas Receiving Reduced-Intensity Conditioning (RIC) Regimen Followed by Allogeneic Stem Cell Transplantation (Allo-SCT): An Update of the Phase II Study of the Gruppo Italiano Trapianto Di Midollo Osseo (GITMO).

Abstract

Long-Term Immunological Profile and T Cell Dynamics In Patients Treated With Allogeneic Transplantation and TK-Cells For Hematological Malignancies

Abstract

Long-Term Immunological Profile of Patients Treated with Haploidentical HSCT and TK-Cells to Study the Requirements of Memory T Cell Persistence

Abstract

Long-lasting CCR5 internalization by antibodies in a subset of long-term non progressors: a possible protective effect against disease progression

Articolo

Long-term remissions after FCR chemoimmunotherapy in previously untreated patients with CLL: Updated results of the CLL8 trial

Articolo

Long-term safety and efficacy of stem cell gene therapy for ADA-SCID.

Abstract

Loss of Mismatched HLA At Leukemia Relapse After Hematopoietic Stem Cell Transplantation Is Significantly Associated with Clinical and Immunogenetic Hallmarks of Donor-Versus-Host Alloreactivity

Abstract

Loss of Mismatched HLA as a Mechanism of Leukemia Immune Escape in Family Haploidentical and Unrelated HSCT: Analysis of 103 Transplants From Alternative Donors

Contributo in Atti di convegno

Loss of the Histone Demethylase UTX Contributes to Multiple Myeloma and Sensitizes Cells to EZH2 Inhibitors

Abstract

Low hepcidin accounts for the proinflammatory status associated with iron deficiency

Articolo

Low-Dose Antithymocyte Globulin, Post-Transplant Cyclophosphamide and Sirolimus As Graft-Versus-Host Disease Prophylaxis in Unrelated Donor Transplants

Abstract

MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program

Articolo

MINIMAL RESIDUAL DISEASE-DRIVEN TREATMENT INTENSIFICATION WITH SEQUENTIAL ADDITION OF IBRUTINIB TO VENETOCLAX IN R/R CLL

Articolo

MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program

Articolo

Male Gender, Quality of Grafted Cells, Advanced Age, Rituximab and Radiotherapy Are the Main Factors That Variously Influence the Occurrence of Secondary Malignancies Following High-Dose Therapy and Autograft: A GITIL (Gruppo Italiano Terapie Innovative nei Linfomi) Survey in 1,347 Lymphoma Patients

Abstract

Mapping the Evolution of the Mutational Landscape of Acute Myeloid Leukemia from Diagnosis to Post-Transplantation Relapse and Its Interplay with Immune Evasion Mechanisms

Abstract

Matching for the nonconventional MHC-I MICA gene significantly reduces the incidence of acute and chronic GVHD

Articolo

Matching of MHC Class I Chain-Related Genes a and B Is Associated with Reduced Incidence of Severe Acute Graft-Versus-Host Disease after Unrelated Hematopoietic Stem Cell Transplantation

Abstract

Mechanisms of immune escape after allogeneic hematopoietic cell transplantation

Articolo

Memory T Cells Masquerading as Naive Cells: Implications on Adoptive T Cell Immunotherapy

Poster

MicroRNA and proliferation control in chronic lymphocytic leukemia: functional relationship between miR-221/222 cluster and p27

Articolo

Microbiome Markers are Early Predictors of Acute GvHD in Allogeneic Hematopoietic Stem Cell Transplant recipients

Articolo

Microcytic anemia and hepatic iron overload in a child with compound heterozygous mutation in DMT1 (SCL11A2)

Articolo

Microvessel density is an independent predictor of survival in multiple myeloma patients.

Abstract

Minimal residual disease (MRD) and risk-oriented therapy in adult acute lymphoblastic leukemia (ALL)

Articolo

Minimal residual disease (MRD)-oriented therapy of adult, acute lymphoblastic leukemia (ALL): Final results of northern Italy leukemia group study 09/00

Articolo

Mitochondrial ferritin expression and clonality of hematopoiesis in patients with refractory anemia with ringed sideroblasts.

Abstract

Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

Articolo

Mitochondrial ferritin expression in the erythroblasts of normal subjects and patients with sideroblastic anemia.

Abstract

Modeling Antileukemic Adoptive immunotherapy In Mouse-Humans Chimeras To Identify Novel Mechanisms Of Cancer Immunoediting

Abstract

Modeling the genotoxicity of viral vector integration in a tumor prone hematopoietic stem cell transplantation model.

Abstract

Modulation of graft-versus-host disease induced by central memory suicide gene modified human T lymphocytes

Articolo

Molecular -thalassemia intermedia in patients of Italian descent andcharacterization of -thalassemia mutations.identification of three novel

Articolo

Molecular characterization of Black HPFH type I in a patient from Cuba

Articolo

Molecular characterization of the t(2;5)(p23;q35) translocation in anaplastic large cell lymphoma (Ki-1) and Hodgkin's disease

Articolo

Molecular follow-up in gastric mucosa-associated lymphoid tissue lymphomas: early analysis of the LY03 cooperative trial

Articolo

Molecular follow-up of patients treated with HSV-TK/Delta LNGFR engineered donor lymphocytes after allogeneic stem cell transplantation

Abstract

Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia

Articolo

Molecular modification of idiotypes from B-cell lymphomas for expression in mature dendritic cells as a strategy to induce tumor-reactive CD4(+) and CD8(+) T-cell responses

Articolo

Molecular remission can be attained in relapsed or refractory chronic lymphocytic leukemia (CLL) and follicular lymphomas after reduced intensity conditioning (RIC) and allogeneic stem cell transplantation (allo-SCT).

Articolo

Monitoring of Wilms' Tumor Gene 1 Levels Predict Early Relapse After Allogeneic Hematopoietic Stem Cells Transplantation in Patients with High Risk Acute Myeloid Leukemia and Myelodysplastic Syndrome

Abstract

Monoclonal B-cell lymphocytosis in healthy blood donors: an unexpectedly common finding

Articolo

Monoclonal B-cell lymphocytosis: right track or red herring?

Articolo

Monoclonal CD5(+) and CD5(-) B-lymphocyte expansions are frequent in the peripheral blood of the elderly

Articolo

Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy

Articolo

Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with rituximab-CHOP: a report from an International DLBCL Rituximab-CHOP Consortium Program study.

Articolo

Mutations in Multiple Genes Cause Deregulation of the NFkB Pathway in Diffuse Large B-Cell Lymphoma

Abstract

Myeloma and DNA damage

Articolo

Mysteries of Mitochondrial Ferritin

Abstract

NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: Dynamics and clinical implications

Articolo

NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD

Abstract

Natural History of congenital dyserythropoietic anemia type II

Articolo

Naturally occurring C-terrainally truncated STAT5 is a negative regulator of HIV-1 expression

Articolo

Neutrophils phagocytose activated platelets in vivo: a phosphatidylserine, P-selectin, and beta 2 integrin-dependent cell clearance program

Articolo

New Mutations inactivating transferring receptor 2 in Hemochromatosis type 3

Articolo

Non-HFE hemochromatosis: insights into regulation of iron metabolism from novel iron loading disorders

Articolo

Non-Linear Clonal Evolution Of Leukemia Driven By Selective Immune Pressure and Revealed By HLA Typing and High-Depth Exome Sequencing

Abstract

Non-TBI conditioning for family haploidentical allogeneic stem cell transplantation: A single centre experience in 20 patients.

Articolo

Nongastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue

Articolo

Nongenomic effects of 17beta-estradiol in human platelets: potentiation of thrombin-induced aggregation through estrogen receptor beta and Src kinase

Articolo

Nonmyeloablative conditioning followed by allogeneic transplantation has a better outcome than high-dose chemotherapy plus autografting in non Hodgkin lymphomas with T-cell histology.

Articolo

Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer

Articolo

Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantation

Articolo

Nonrelapse-related mortality (NRM) among 1,201 adult patients with acute leukemia treated over a 23 year period.

Articolo

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

Articolo

Novel Mouse Models of Chronic Lymphocytic Leukemia (CLL) Unravel the Molecular Mechanisms Controlling Bone Marrow Involvement by Leukemic B Cells

Abstract

Novel structurally altered P(2X1) receptor is preferentially activated by adenosine diphosphate in platelets and megakaryocytic cells.

Articolo

Nucleotide insertions and deletions in chronic lymphocytic leukemia. A CLL specific deletion among IGHV3-21 expressing cases with stereotyped receptors

Abstract

Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease

Articolo

Outcome of hematopoietic stem cell transplantation for adenosine deaminase deficient severe combined immunodeficiency

Articolo

Outcome of patients with distinct molecular genotypes and cytogenetically normal AML after allogeneic transplantation

Articolo

Outcomes of patients with hematologic malignancies and COVID-19: A systematic review and meta-analysis of 3377 patients

Articolo

Outcomes of unrelated cord blood and haploidentical stem cell transplantation in adults with acute leukaemia.

Articolo

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations

Articolo

Over 30% of Patients with Splenic Marginal Zone Lymphoma Express Distinctive Antigen Receptors Utilizing a Single Immunoglogulin Variable Gene: Implications for the Origin and Selection of the Neoplastic Cells

Abstract

PCM1-JAK2 Fusion Product Selectively Activates MAP-Kinase Pathway and Fails to Phosphorylate JAK2 and STAT5: Implications for Therapeutic Strategies

Abstract

PHENOTYPIC AND FUNCTIONAL-ANALYSIS OF T-CELL PRECURSORS IN THE HUMAN FETAL LIVER AND THYMUS - CD7 EXPRESSION IN THE EARLY STAGES OF T-CELL AND MYELOID-CELL DEVELOPMENT

Articolo

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

Articolo

Pathologic findings in lymph nodes in a patient with autoimmune lymphoproliferative syndrome (ALPS) who developed a histiocyte-rich/T-cell-rich B cell lymphoma: Evolution during a 20-year follow-up.

Abstract

Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair

Articolo

Patients with aaIPI 2-3 diffuse large B-cell lymphoma achieve 75% long-term survival following first-line rituximab-supplemented high-dose sequential chemotherapy and autograft: Final results of the prospective phase II GITIL (Gruppo Italiano Terapie Innovative nei Linfomi) trial.

Articolo

Pediatric-Type Therapy Including Lineage-Targeted Methotrexate to Improve Early Minimal Residual Disease Response and Survival In Adult Acute Lymphoblastic Leukemia (ALL): Interim Analysis of Northern Italy Leukemia Group Study 10/07.

Abstract

Peripheral blood stem cells allograft rejection by CD4* T lymphocytes recognizing a single mismatch at HLA-DPS1*0901

Articolo

Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer

Articolo

Peripheral blood lymphocytes genetically modified to express the self/tumor antigen MAGE-A3 induce antitumor immune responses in cancer patients

Articolo

Phenotypic and functional evidence for the expression of CD4 by hematopoietic stem cells isolated from human fetal liver

Articolo

Phorbol ester-induced PKC{epsilon} down-modulation sensitizes AML cells to TRAIL-induced apoptosis and cell differentiation

Articolo

Plant homologue constitutive photomorphogenesis 9 (COP9) signalosome subunit CSN5 regulates innate immune responses in macrophages

Articolo

Platelet activation (PA) in myelodysplastic syndromes (MDS's): Flow cytometric analysis with CD62 (P-selectin) monoclonal antibody (MAb).

Articolo

Platelets mediate clearance of lymphocytic choriomeningitis virus infection preventing lethal hemorrhage

Abstract

Platelets mediate cytotoxic T lymphocyte-induced liver damage

Abstract

Post-Chemotherapy Brain Irradiation in Primary CNS Lymphomas: Impact on Survival of Different Fields and Doses.

Abstract

Postgenomic up-regulation of CCL3L1 expression in HTLV-2-infected persons curtails HIV-1 replication

Articolo

Posttransplantation cyclophosphamide and sirolimus for prevention of GVHD after HLA-matched PBSC transplantation

Articolo

Predicting outcomes in CNS lymphoma with ctDNA

Articolo

Predictors of response and survival in primary central nervous system lymphoma (PCNSL): Analysis of an international multicentre series of 378 immunocompetent patients.

Abstract

Preexisting and treatment-emergent autoimmune cytopenias in patients with CLL treated with targeted drugs

Articolo

Prenatal Diagnosis of fetal hemoglobin Lepore-Boston Disease on maternal peripheral blood

Articolo

Primary and prolonged isolated involvement of bone marrow by Hodgkin Disease in HIV infected patients.

Abstract

Primary central nervous system lymphoma of T cell origin: A descriptive analysis of 45 cases from the International PCNSL Collaborative Group.

Abstract

Profiling the Genomic Landscape at the Early Stages of CLL: Low Genomic Complexity and Paucity of Driver Mutations in MBL and Indolent CLL

Abstract

Prognostic relevance of MYD88 mutations in CLL: the jury is still out

Articolo

Prognostic value of positron emission tomography (PET) scan in patients with relapsed Hodgkin lymphoma or aggressive Non-Hodgkin lymphoma receiving salvage chemotherapy followed by reduced-intensity allogeneic stem cell transplantation

Articolo

Programmed infusions of Tk-transduced donor lymphocytes for immune reconstitution and relapse prevention in haplo-identical T-depleted SCT.

Articolo

Prolonged survival of lymphoma patients achieving complete remission following high-dose sequential chemotherapy and autograft (HDS program): A GITIL (Gruppo Italiano Terapie Innovative nei Linfomi) retrospective study on 1,266 patients.

Articolo

Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietec cells

Articolo

Proplatelet generation in the mouse requires PKC{varepsilon}-dependent RhoA inhibition

Articolo

Prospective assessment of NGS-detectable mutations in CML patients with nonoptimal response: The NEXT-in-CML study

Articolo

Proteasome Activity Restricts Lentiviral Gene Transfer in Hematopoietic Stem Cells and is Down-Regulated by Cytokines that Enhance Transduction

Articolo

Protein Kinase C Epsilon Inhibition Restores In-Vitro Megakaryocyte Differentiation Of Primary Myelofibrosis Hematopoietic Progenitors

Abstract

R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma

Articolo

RNA SILENCING OF THE MITOCHONDRIAL ABCB7 TRANSPORTER IN HELA CELLS CAUSES AN IRON-DEFICIENT PHENOTYPE WITH MITOCHONDRIAL IRON OVERLOAD

Articolo

Randomized Phase II Trial on Primary Chemotherapy with High-Dose Methotrexate Alone or Associated with High-DoseCytarabine for Patients with Primary CNS Lymphoma (IELSG #20 Trial): Tolerability, Activity and Event-Free Survival Analysis

Articolo

Rapamycin selectively expands CD4(+)CD25(+)FoxP3(+) regulatory T cells

Articolo

Rapamycin-Based GvHD Prophylaxis Is Effective in T-Cell Replete Unmanipulated Haploidentical Peripheral Stem Cell Transplantation for Advanced Haematological Malignancies: Results in 46 Patients

Contributo in Atti di convegno

Rapid Molecular Detection of Pathogens in 516 Consecutive Haematological Patients with Febrile Neutropenia

Abstract

Rapid and ride immunereconstitution obtained with HSV-TK engineered donor lymphocyte add-backs permits long-term survival after haplo-HSCT.

Articolo

Recent advances in understanding the pathophysiology of wiskott-aldrich syndrome

Articolo

Receptor repertoire reconstitution suggests acquisition of patient-specific tolerance by natural killer cells arising from hematopoietic progenitor stem cells after haploidentical transplantation

Articolo

Recurrent 11q24.3 Gain Contributes to the Pathogenesis of Diffuse Large B Cell Lymphoma (DLBCL) by Deregulating ETS1 and FLI1

Abstract

Reduced intensity conditioned allografts for myeloma: A study from the Chronic Leukaemia Working Party of the EBMT.

Articolo

Reduced intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in leukemias and lymphomas.

Abstract

Reduced-intensity allogeneic stem cell, transplantation in ovarian carcinoma: Preliminary evidence of graft-versus-ovarian cancer effect.

Articolo

Reduced-intensity conditioning (RIC) followed by allogeneic stem cell transplantation (SCT) for relapsed lymphomas: Impact of pre-transplantation factors on long-term outcome.

Articolo

Reduced-intensity conditioning followed by allogeneic transplantation (HSCT) is an effective salvage treatment for both low- and high-grade non-Hodgkin lymphomas: Disease chemosensitivity has a major impact on outcome.

Articolo

Reduced-intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in patients with poor-risk hematologic malignancies

Articolo

Reduced-intensity conditioning with low dose ATG or alemtuzumab followed by allogeneic PBSC: A salvage therapy with an encouraging response rate and limited toxicity in relapsed/refractory multiple myeloma.

Articolo

Refined Disease Risk Index (DRI) and Hematopoietic Cell Transplantation Comorbidity Index (HCT-CI) Predict Survival after Haploidentical Stem Cell Transplantation: A Comparative Study with EBMT Risk Score in 220 Consecutive Patients

Abstract

Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation

Articolo

Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD.

Articolo

Requirements for retroviral targeting of a suicide gene to alloreactive memory stem T cells for adoptive immunotherapy of leukemia

Abstract

Response of monocyte iron regulatory protein activity to inflammation: Abnormal behavior in genetic hemochromatosis

Articolo

Retrospective analysis of HHV-8 viremia and cellular viral load in HIV-seropositive patients receiving interleukin 2 in combination with antiretroviral therapy

Articolo

Retroviral vector integration deregulates gene expression but has no consequences on the biology and function of transplanted T cells.

Articolo

Revealing the Generation of Human Memory Stem T Cells in Haploidentical T-Replete Hematopoietic Stem Cell Transplantation

Abstract

Risk factors for outcomes of family haploidentical allogeneic stem cell transplantation for adults with acute leukemias: A survey on behalf of the acute leukemia working party of the European group for blood and marrow transplantation (EBMT).

Articolo

Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma

Articolo

SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells

Articolo

SNP-Arrays Provide New Insights Into the Pathogenesis of Post-Transplant Diffuse Large B-Cell Lymphoma (PT-DLBCL)

Abstract

SPECIFIC BINDING-SITES FOR H-FERRITIN ON HUMAN-LYMPHOCYTES - MODULATION DURING CELLULAR PROLIFERATION AND POTENTIAL IMPLICATION IN CELL-GROWTH CONTROL

Articolo

Safety and efficacy of rituximab in patients with hepatitis C virus-related mixed cryoglobulinemia and severe liver disease

Articolo

Sardinian delta beta zero-thalassemia: a further example of a C to T substitution at position -196 of the A gamma globin gene promoter.

Articolo

Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R)

Articolo

Second Allogeneic Stem Cell Transplantation (allo-SCT) Using Reduced-Intensity Conditioning (RIC) for Acute Myeloid Leukemia (AML) Patients Who Relapsed Following a First RIC Allo-SCT: a Survey From the Acute Leukemia Working Party of EBMT

Abstract

Selective expression of fos proto-oncogene in human acute myelomonocytic and monocytic leukemias: a molecular marker of terminal differentiation.

Articolo

Selective suppression of IL-12 production by human herpesvirus 6

Articolo

Serine/Threonine Kinase STK4 Is a Novel Target in Myeloma

Abstract

Short regimen of rituximab plus lenalidomide in follicular lymphoma patients in need of first-line therapy

Articolo

Sickle cell disease: An international survey of results of HLA-identical sibling hematopoietic stem cell transplantation

Articolo

Significantly higher frequencies of alloreactive CD4(+) T cells responding to nonpermissive than to permissive HLA-DPB1 T-cell epitope disparities

Articolo

Single cell analysis reveals immune dysfunction from the earliest stages of CLL that can be reversed by ibrutinib

Articolo

Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program

Articolo

Sirolimus and Post Transplant Cyclophosphamide (PT-Cy) Allow the Use of Haploidentical PBSC Grafts Inducing a Favorable Immune Reconstitution with Low Rates of GvHD: Results in 39 Patients

Abstract

Six-Month Doxycycline Is Safe and Effective As Upfront Monotherapy for Stage-I Malt Lymphoma of the Ocular Adnexae: Primary Endpoint Results of the IELSG39 Trial

Abstract

Skewed T-cell receptor repertoire, decreased thymic output, and predominance of terminally differentiated T cells in ataxia telangiectasia

Articolo

Somatic mutations of JAK2 exon 12 in patients with JAK2 (V817F)- negative myeloproliferative disorders

Articolo

Sox6 enhances erythroid differentiation in human erythroid progenitors

Articolo

Standardized Long-Term Follow-up after Allogeneic Stem Cell Transplantation: A Cross-Sectional 1-Year Evaluation in 260 Adults

Abstract

Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

Articolo

Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis

Articolo

Structural, functional and tissue distribution analysis of human transferrin receptor-2 by murine monoclonal antibodies and a polyclonal antiserum

Articolo

Subgroups of Diffuse Large B-Cell Lymphoma (DLBCL) with Different Genomic Lesions and Clinical Course During Treatment with R-CHOP

Abstract

Successful reconstitution of human hematopoiesis in the SCID-hu mouse by genetically modified, highly enriched progenitors isolated from fetal liver

Articolo

Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes

Articolo

Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes.

Abstract

Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis.

Articolo

Survival after T cell depleted haploidentical stem cell transplantation is improved using the mother as donor

Articolo

Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia

Articolo

Synthetic Lethal Approaches to Exploit Replicative Stress in Aggressive Myeloma

Abstract

T Cell Receptor Gene Transfer into Naive and Central Memory Lymphocytes by Lentiviral Vectors for a Safe and Effective Adoptive Immune Therapy of Leukemia

Abstract

T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression

Abstract

T cells dressed up with a dual HLA-restricted TCR targeting cathepsin G drive effective AML eradication

Articolo

T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency

Articolo

T-cell suicide gene therapy prompts thymic renewal in adults after hematopoietic stem cell transplantation

Articolo

TCR Gene Editing Results in Effective Immunotherapy of Leukemia without the Development of GvHD

Abstract

TK-Cells Safety and Efficacy in Allogeneic Hematopoietic Stem Cell Transplantation: Long-Term Clinical and Molecular Assessment in 128 Treated Patients

Abstract

TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals.

Articolo

TRANSFER OF THE HSV-TK GENE INTO DONOR PERIPHERAL-BLOOD LYMPHOCYTES FOR IN-VIVO IMMUNOMODULATION OF DONOR ANTITUMOR IMMUNITY AFTER ALLO-BMT

Abstract

Targeting B-cell anergy in chronic lymphocytic leukemia.

Articolo

Targeting PKC: A Novel Role for Beta-catenin in ER Stress and Apoptotic Signaling

Abstract

Targeting PKC: A novel role for beta-catenin in ER stress and apoptotic signaling

Articolo

Targeting Replicative Stress to Treat Hematological Disorders

Abstract

Targeting cholesterol homeostasis in hematopoietic malignancies

Articolo

Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody

Articolo

Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

Articolo

Targeting proteinkinase C alters ER-stress and b-catenin signaling in multiple myeloma: Therapeutic implications

Abstract

Targeting the BMP Receptor Inhibitor FKBP12 to Upregulate Hepcidin in Wild-Type and Hemojuvelin-Hemochromatosis Models

Abstract

Targeting the LYN/HS1 signaling axis in chronic lymphocytic leukemia

Articolo

Temporal, quantitative and functional characteristics of Single-KIR positive alloreactive NK cell recovery account for impaired graft versus leukemia activity after haploidentical HSCT

Articolo

Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation

Articolo

The "cutaneous variant" of intravascular lymphomatosis (IVL) is a favorable clinical form in western countries: A clinico-pathologic study on 31 cases.

Abstract

The AP-1 Transcription Factor JunB Promotes Multiple Myeloma (MM) Cell Proliferation, Survival and Drug Resistance in the Bone Marrow Microenvironment

Abstract

The Deubiquitinase Activity of CYLD Is Required for Maturation of B Cells

Abstract

The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro

Articolo

The Hidden (And Lazy) TCR

Articolo

The Importance of Be(ginn)Ing Naive: Implications for Cancer Immune-Gene Therapy

Poster

The MEK1/2 inhibitor AZD6244 (ARRY-142886) downregulates constitutive and adhesion-induced c-MAF oncogene expression and its downstream targets in human multiple myeloma

Abstract

The NF-kappa B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas

Articolo

The Oncogene MYC Triggers Replicative Stress and DNA Damage In Multiple Myeloma

Abstract

The Role of the ABL1/YAP1/P73 Axis in Prevention of DNA Damage-Mediated Apoptosis in Multiple Myeloma

Abstract

The amyloidogenic light chain is a stressor that sensitizes plasma cells to proteasome inhibitor toxicity

Articolo

The expression of cyclin-dependent kinase (cdk) inhibitor p27(KIP1) and cyclin E is an independent survival predictor in stage I-II primary gastric B-cell lymphomas (PGL).

Abstract

The fate of gene modified T-cells can be followed in 2 patients without immunosuppression after allogeneic stem cell transplantation.

Articolo

The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche

Articolo

The genetics of nodal marginal zone lymphoma

Articolo

The homozygous state of G to A--117A gamma hereditary persistence of fetal hemoglobin

Articolo

The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload

Articolo

The immune response to lentiviral-delivered transgene is modulated in vivo by transgene expressing antigen presenting cells but not by CD4+CD25+ regulatory T cells

Articolo

The immunoglobulin gene repertoire of low-count chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis is different from CLL: diagnostic implications for clinical monitoring

Articolo

The influence of purified recombinant human heavy-subunit and light-subunit ferritins on colony formation in vitro by granulocyte-macrophage and erythroid progenitor cells.

Articolo

The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells

Articolo

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

Articolo

The mitochondrial protease ClpP is a metabolic vulnerability and an immunogenic trigger against multiple myeloma

Articolo

The neovasculature homing motif NGR: more than meets the eye

Articolo

The pattern of CD38 expression defines a distinct subset of chronic lymphocytic leukemia (CLL) patients at risk of disease progression

Articolo

The pattern recognition receptor PTX3 is recruited at the synapse between dying and dendritic cells, and edits the cross-presentation of self, viral, and tumor antigens

Articolo

The phase 3 DUO trial: Duvelisib vs ofatumumab in relapsed and refractory CLL/SLL

Articolo

The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies

Articolo

The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition

Articolo

The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications

Articolo

The relationship between anemia, fecal stercobilinogen erythrocyte survival, and globin synthesis in heterozygotes for beta-thalassemia

Articolo

The risk of secondary myelodysplastic syndrome/acute leukemia following intensive therapy and autograft correlates with the type of cells grafted: A survey on 1,347 lymphoma patients receiving the high-dose sequential (HDS) program.

Articolo

The second transferrin receptor regulates red blood cell production in mice

Articolo

The small-molecule VEGF-receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma

Abstract

The spectrum of hemojuvelin gene mutations in 1q-linked Juvenile Hemochromatosis

Articolo

The t(14;18)(q32;q21) Characterizes a Subset of Patients with Diffuse Large-B Cell Lymphoma of Germinal Center Origin with Poor Outcome: Report From the International DLBCL Rituximab-CHOP Consortium Program Study

Abstract

Theoretical Availability of UCBT in High Body Weight Patients Who Received Haplo-SCT for High Risk Haematological Malignancies: Results of the Simulation of Search through BMDW According to International Guidelines

Abstract

Therapeutic management of immunocompetent patients with primary central nervous system lymphoma (PCNSL): Analysis of an International Multicentre Series of 378 patients.

Abstract

Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration

Articolo

Thymic Renewal and Anti-Leukemic Effect In Adults After Haploidentical Transplantation and Donor T Cell Suicide Gene Therapy

Abstract

Time of Origin and Environmental Drivers of Leukemia Immune Escape after Transplantation

Abstract

Timing of high-dose methotrexate CNS prophylaxis in DLBCL: a multicenter international analysis of 1384 patients

Articolo

Tolerogenic dendritic cells: cytokine modulation comes of age

Articolo

Transcription Factor Binding Sites Are Genetic Determinant of Retroviral Integration in the Human Genome

Contributo in Atti di convegno

Transcriptional targeting of retroviral vectors to the erythroblastic progeny of transduced hematopoietic stem cells

Articolo

Transfer of the ADA gene into human ADA-deficient T Lymphocytes reconstitutes specific immune functions

Articolo

Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis

Articolo

Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: Evidence from a murine model

Articolo

Treosulfan-based conditioning for allogeneic HSCT in children with chronic granulomatous disease: A multicenter experience

Articolo

Trick to treat: tricking the thymus to treat cancer

Articolo

Tricking the trickster: precision medicine approaches to counteract leukemia immune escape after transplant

Articolo

Tumor-associated macrophages as major source of APRIL in gastric MALT lymphoma

Articolo

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome

Articolo

Unbalanced expression of bcl-2 family proteins in follicular lymphoma: Contribution of CD40 signaling in promoting survival

Articolo

Uncovering Haematopoietic System Dynamics and Single Multipotent Progenitors Activity In Vivo In Humans by Retroviral Tagging

Abstract

Understanding iron homeostasis through genetic analysis of haemochromatosis and related disorders

Articolo

Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans

Articolo

Up-regulation of c-Jun contributes to induction of apoptosis by Adaphostin in human multiple myeloma cells

Abstract

Update of a GITIL cohort study: Frontline high dose sequential chemotherapy with rituximab and autologous stem cell transplantation induces a high rate of long-term remissions in patients with mantle cell lymphoma

Articolo

Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency

Articolo

Upregulation of c-Jun induces cell death via caspase-triggered c-Abl cleavage in human multiple myeloma

Abstract

Use of a DNAemia cut-off for monitoring human cytomegalovirus infection reduces the number of preemptively treated children and young adults receiving hematopoietic stem-cell transplantation compared with qualitative pp65 antigenemia

Articolo

Vinculin, talin, and integrins are localized at specific adhesion sites of malignant B lymphocytes

Articolo

WHO classification and WPSS predict posttransplantation outcome in patients with myelodysplastic syndrome: A study from the Gruppo Italiano Trapianto di Midollo Osseo (GITMO)

Articolo

Wild-type FOXP3 is selectively active in CD4(+)CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations

Articolo

Wiskott-Aldrich syndrome: a study of 577 patients defines the genotype as a biomarker for disease severity and survival

Articolo

Younger unrelated donors may be preferable over HLA match in the PTCy era: a study from the ALWP of the EBMT

Articolo

ZUMA-8: a phase 1 study of brexucabtagene autoleucel in patients with relapsed/refractory chronic lymphocytic leukemia

Articolo

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ+/CD19+ lymphocytes

Articolo

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Pubblicazioni (559)