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Iron Administration Overcomes Resistance to Erastin-Mediated Ferroptosis in Ovarian Cancer Cells

Academic Article
Publication Date:
2022
abstract:
Developing novel therapeutic approaches to defeat chemoresistance is the major goal of ovarian cancer research. Induction of ferroptosis has shown promising antitumor effects in ovarian cancer cells, but the existence of still undefined genetic and metabolic determinants of susceptibility has so far limited the application of ferroptosis inducers in vivo.
Iris type:
1.1 Articolo in rivista
Keywords:
chemoresistance; erastin; ferroptosis; iron; mitochondrial dysfunction; ovarian cancer
List of contributors:
Battaglia, Anna Martina; Sacco, Alessandro; Perrotta, Ida Daniela; Faniello, Maria Concetta; Scalise, Mariangela; Torella, Daniele; Levi, Sonia; Costanzo, Francesco; Biamonte, Flavia
Authors of the University:
LEVI SONIA MARIA ROSA
Handle:
https://iris.unisr.it/handle/20.500.11768/130231
Published in:
FRONTIERS IN ONCOLOGY
Journal
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