Profiling morphologic MRI features of motor neuron disease caused by TARDBP mutations
Academic Article
Publication Date:
2022
Short description:
Profiling morphologic MRI features of motor neuron disease caused by TARDBP mutations / Spinelli, E.G., Ghirelli, A., Riva, N., Canu, E., Castelnovo, V., Domi, T., Pozzi, L., Carrera, P., Silani, V., Chiò, A., Filippi, M., Agosta, F.. - In: FRONTIERS IN NEUROLOGY. - ISSN 1664-2295. - 13:(2022). [10.3389/fneur.2022.931006]
abstract:
Mutations in the TARDBP gene are a rare cause of genetic motor neuron disease (MND). Morphologic MRI characteristics of MND patients carrying this mutation have been poorly described. Our objective was to investigate distinctive clinical and MRI features of a relatively large sample of MND patients carrying TARDBP mutations.
Iris type:
1.1 Articolo in rivista
Keywords:
amyotrophic lateral sclerosis (ALS); magnetic resonance imaging (MRI); motor neuron disease (MND); transactive response (TAR) DNA binding protein 43 (TARDBP); voxel-based morphometry (VBM)
List of contributors:
Spinelli, Edoardo Gioele; Ghirelli, Alma; Riva, Nilo; Canu, Elisa; Castelnovo, Veronica; Domi, Teuta; Pozzi, Laura; Carrera, Paola; Silani, Vincenzo; Chiò, Adriano; Filippi, Massimo; Agosta, Federica
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