Comparative analysis of visual outcomes with two enhanced monofocal intraocular lenses

Purpose: To compare the visual performance, spectacle independence and subjective visual quality of two enhanced monofocal intraocular lenses (IOL): Eyhance ICB00 and ZOE Primus-HD. Setting: Ophthalmology Department, San Raffaele Scientific Institute, Milan, Italy. Design: Prospective case series. Methods: We included patients without ocular comorbidities and corneal astigmatism <0.75 diopters (D) undergoing cataract surgery with bilateral implantation of enhanced monofocal Eyhance and ZOE. Six months postoperatively we analyzed the following parameters: subjective and objective refraction; monocular and binocular corrected distance (4 m) and uncorrected distance visual acuity (UDVA); corrected distance, intermediate (66 cm) and near (40 cm) visual acuity, as well as uncorrected intermediate (UIVA) and uncorrected near (UNVA) visual acuity; photopic contrast sensitivity, binocular defocus curve; halo and glare perception; spectacle independence. Results: We evaluated 100 eyes of 50 patients (25 patients per IOL group). The two IOLs showed superimposable visual performances, without significant differences in terms of refractive and visual outcomes, defocus curves, contrast sensitivity, scores of vision quality and spectacle independence. Of note, monocular and binocular UDVA was excellent in both groups. The 2 IOL models achieved satisfactory binocular UIVA, with more than 70% of patients reaching a binocular UIVA ≤0.1 logMAR. Up to 84% of patients eventually declared to feel comfortable frequently while staying at intermediate distance. Conclusions: The general visual outcome of the Eyhance ICB00 and the ZOE Primus-HD enhanced monofocal intraocular lenses are similar, with special reference to the satisfactory spectacle independence for intermediate distance.