Intrasphincteric injection of botulinum toxin is effective in long-term treatment of esophageal achalasia
Academic Article
Publication Date:
1998
Short description:
Intrasphincteric injection of botulinum toxin is effective in long-term treatment of esophageal achalasia / Annese, V., Basciani, M., Borrelli, O., Leandro, G., Simone, P., Andriulli, A.. - In: MUSCLE & NERVE. - ISSN 0148-639X. - 21:11(1998), pp. 1540-1542. [10.1002/(SICI)1097-4598(199811)21:11<1540::AID-MUS27>3.0.CO;2-2]
abstract:
We investigated the long-term efficacy and safety of intrasphincteric injections of botulinum toxin (100 U) in 57 patients with esophageal achalasia. One month after treatment, 50 patients had improved (88%); both symptom score and LES pressure were significantly reduced (P < 0.001). After a mean follow-up of 24 ± 15 months (range 6-48), 43 patients (75%) are still in remission, although repeat injections of toxin were needed to achieve a stable effect on symptoms.
Iris type:
1.1 Articolo in rivista
List of contributors:
Annese, V.; Basciani, M.; Borrelli, O.; Leandro, G.; Simone, P.; Andriulli, A.
Published in: