Platelet-leukocyte interactions

The current vision of the mechanisms involved in the hemostasis, inflammation, and innate immunity is based on the intricate interplay between platelets and leukocytes. However, were necessary about three decades to abate the paradigm in which leukocytes are involved only in the immune response and platelets only in the hemostasis. In this chapter, we try to illustrate the clinical and experimental evidences of the wealthy crosstalk between platelets and leukocytes that support real insight into the function of these cells.