The future of transpathology

Postmortem tissue analysis offers high spatial resolution for structural and molecular information. However, it is limited to selective probing of tissue through biopsies and surgical samples. To bridge the gap between in vivo and ex vivo data, the emerging field of “transpathology” is gaining attention. This field aims to guide biopsy and surgical interventions, linking information from both realms with varying spatial resolutions and types of biological data. Transpathology, through pathophysiological visualization, facilitates precise diagnoses, prognostic predictions, and personalized treatments. This field has the potential to revolutionize disease diagnosis and treatment, presenting a promising future.