Mesenchymal Stem Cells in Dental Applications: State of the Art and Future Insights

Studies on stem cells have demonstrated their capacity for organ and tissue repair with their self-renewal and differentiation features. They produce different cell types, thus providing new strategies for regenerating missing tissues and treating more diseases. Adult mesenchymal stem/stromal cells (MSCs) have been identified in several oral and maxillofacial tissues and, adequately reprogrammed, induced pluripotent stem (iPS) cells, providing an ideal source for new bio-technologies and tissue engineering, for novel tools for reconstructive surgery with regard to clinical availability and applications in dentistry.