Dystrophy-Related Choroidal Neovascularization

Choroidal neovascularization (CNV) represents a possible complication of hereditary chorioretinal dystrophies. Compared to the more common clinical picture of age-related macular degeneration, CNVs associated with hereditary chorioretinal dystrophies occur in younger subjects and increase significantly the risk of severe impairment of the central visual function, especially in retinal disorders with primary involvement of the macular area.As observed in CNV associated with age-related macular degeneration or pathological myopia, the advent of anti-VEGF drug therapy has provided a more reassuring perspective on the evolution of the disease and the efficacy of the therapy. This chapter reviews the less prevalent reports of CNV related to hereditary chorioretinal dystrophies and pools evidence on the success and limitations of a variety of therapies.