Publication Date:
2013
abstract:
AIMS: The aim of this study was to investigate whether the shelf-life of
diagnostic antibodies is longer than the expiry date on the label.
METHODS AND RESULTS: Four independent laboratories tested a small number of
diagnostic antibodies kept at +4°C for 12-26 years, and found them to work
perfectly on routine histology sections.
CONCLUSIONS: Diagnostic antibodies may have a workable half-life in excess of 10
years, and the emphasis on performance should shift to the preservation of
antigenic targets in the tissue.
diagnostic antibodies is longer than the expiry date on the label.
METHODS AND RESULTS: Four independent laboratories tested a small number of
diagnostic antibodies kept at +4°C for 12-26 years, and found them to work
perfectly on routine histology sections.
CONCLUSIONS: Diagnostic antibodies may have a workable half-life in excess of 10
years, and the emphasis on performance should shift to the preservation of
antigenic targets in the tissue.
Iris type:
1.1 Articolo in rivista
List of contributors:
Argentieri, Mc; Pilla, D; Vanzati, A; Lonardi, S; Facchetti, F; Doglioni, Claudio; Parravicini, C; Cattoretti, G.
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