P3170Innovative approach for risk stratification of LMNA-related cardiomyopathy: results from an integrated cardiological and neurological 10-year follow-up multicentre study

Methods: 164 LMNA mutation carriers (median age 38 y; 51.2% females) were enrolled from 13 referral centers. All of them underwent a combined C and N assessment at the time of enrollment and 2/y for 10 y median FU, including ECG, Holter monitoring, and imaging data. Further detailed clinical information were collected retrospectively. The purpose of the study was to describe natural history of the disease and to stratify cardiac risk based on an innovative multispecialistic approach.