Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer
Academic Article
Publication Date:
2011
Short description:
Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer / Kalimutho, M., Del Vecchio Blanco, G., Di Cecilia, S., Sileri, P., Cretella, M., Pallone, F., Federici, G., Bernardini, S.. - In: JOURNAL OF GASTROENTEROLOGY. - ISSN 0944-1174. - 46:12(2011), pp. 1391-1402. [10.1007/s00535-011-0456-0]
abstract:
MicroRNAs (miRNA) are tiny, noncoding, small, endogenous RNAs that play major roles in neoplastic transformation and could therefore offer a better quantitative and noninvasive method for the diagnosis and prognosis of colorectal cancer (CRC) using feces. In the present study, we screened feces for 648 miRNAs and analyzed the role of miR-144* as a potential CRC diagnostic marker.
Iris type:
1.1 Articolo in rivista
Keywords:
Sensitivity and Specificity; MicroRNAs; Humans; Temperature; Aged; Reverse Transcriptase Polymerase Chain Reaction; Gene Expression Regulation; Neoplastic; Aged; 80 and over; Adult; Middle Aged; Feces; Tumor Markers; Biological; Time Factors; Colorectal Neoplasms; Female; Male
List of contributors:
Kalimutho, M; Del Vecchio Blanco, G; Di Cecilia, S; Sileri, P; Cretella, M; Pallone, F; Federici, G; Bernardini, S
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