Diagnostic performance of Endoscopic Ultrasound Through-The-Needle microforceps Biopsy (EUS-TTNB) of pancreatic cystic lesions: a systematic review with meta-analysis

Endoscopic ultrasound through-the-needle biopsy (EUS-TTNB) is a useful tool for differential diagnosis among pancreatic cystic lesions (PCLs). Cystic fluid cytology (CFC) is recommended by guidelines, but its diagnostic accuracy is about 50%. The aim of this meta-analysis is to assess the clinical impact of EUS-TTNB in terms of technical success (TS), histological accuracy (HA) and diagnostic yield (DY).