Histologic Subtype, Tumor Grade, Tumor Size, and Race Can Accurately Predict the Probability of Synchronous Metastases in T2 Renal Cell Carcinoma

Synchronous metastases have varied significantly according to the histologic subtype, tumor grade, and tumor size in patients with stage T2 renal cell carcinoma. Both histologic subtype and tumor grade can be highly accurately derived from renal mass biopsy before planned nephrectomy. This knowledge could allow one to tailor the risk before the nephrectomy metastatic evaluation, according to histologic subtype, tumor grade, tumor size, and race.