Person
Attachment (CV)
Mirela Kuka CV Feb 2026.pdf (Curriculum Vitae Mirela Kuka)
Description
CURRENT POSITION
2024 - Present Associate Professor of Pathology (MEDS-02/A)
School of Medicine
Vita-Salute San Raffaele University, Milan (Italy)
2025 - 2037 National Scientific Qualification (ASN)
Full Professor of Pathology (MEDS-02/A)
2023 - Present Project Leader
Division of Immunology, Transplantation and Infectious Diseases
San Raffaele Scientific Institute, Milan (Italy)
INSTITUTIONAL RESPONSABILITIES
2025 – Present
Vice President of the Bachelor’s Degree in Biotechnology Research in Medicine
Vita-Salute San Raffaele University (Milan, Italy)
2024 – Present
Coordinator of the PhD Curriculum in Basic and Applied Immunology and Oncology
International PhD Program in Molecular Medicine
Vita-Salute San Raffaele University (Milan, Italy)
PAST WORK EXPERIENCE
2021 - 2024 Assistant Professor of Pathology (RTDB MED/04)
2016 - 2021 Researcher and Lecturer of Pathology (RTDA MED/04)
School of Medicine
Vita-Salute San Raffaele University, Milan (Italy)
2016 - 2023 Young Principal Investigator
2013 - 2016
Senior Postdoctoral Fellow
Dynamics of Immune Responses Unit (Head Prof. Matteo Iannacone)
Division of Immunology, Transplantation and Infectious Diseases
San Raffaele Scientific Institute, Milan (Italy)
2010 - 2013 Postdoctoral Fellow
Laboratory of Immune Cell Biology (Head Dr. Jonathan D. Ashwell)
National Cancer Institute (NCI)
National Institutes of Health, Bethesda (Maryland, US)
2006 - 2010
Ph.D Student/Research Fellow
Adjuvants Team (Head Dr. Ugo D’Oro)
Department of Immunology
Novartis Vaccines and Diagnostics, Siena (Italy)
Collaborative Ph.D. program between University of Siena, Novartis Vaccines and Diagnostics, and the FP6 Network of Excellence DC-THERA
2003 - 2006
Undergraduate Student (Bachelor and Master Thesis)
Department of Clinical and Biological Sciences (Supervisor Prof. Giuseppe Saglio)
University of Turin, San Luigi Hospital, Orbassano (Italy)
2003
Undergraduate Student (Internship)
Department of Genetics, Biology and Biochemistry (Supervisor Prof. Mara Brancaccio)
University of Turin, Turin (Italy)
EDUCATION
January 2010
Ph.D. in Cellular and Molecular Biology
School of Evolutionary Biology
University of Siena, Siena (Italy)
July 2006
Master of Science in Molecular Biotechnologies (110/110 cum laude)
University of Turin, Turin (Italy)
July 2004
Bachelor of Science in Biotechnologies (110/110 cum laude)
University of Turin Turin (Italy)
FUNDING
2025 – 2030
AIRC Investigator Grant – 1,200,000 € (PI)
Italian Ministry of University and Research (MUR)
2023 – 2027
Ricerca finalizzata 2021 (Young Researchers) – 225,000 € (Operative Unit PI)
Italian Ministry of Health
2023 – 2025
PRIN 2022 PNRR – 120,000 € (PI)
Italian Ministry of University and Research (MUR)
2022 – 2025
PNRR INF-ACT – Member of the UniSR Team - Spoke 1
Vita-Salute San Raffaele University, Milan (Italy)
2023 – 2024
Research contract (Assegno di ricerca) sponsored by UniSR for the recruitment of a young fellow – 24,000 € (PI)
Vita-Salute San Raffaele University, Milan (Italy)
2022 – 2025
PRIN 2020 – 172,000 € (Local Unit PI)
Italian Ministry of University and Research (MUR)
2019 – 2023
PRIN 2017 – 407,000 € (Local Unit PI)
Italian Ministry of Education, University, and Research (MIUR)
2015 – 2020
Scientific Independence of Young Researchers (SIR) – 539,000 € (PI)
Italian Ministry of Education, University, and Research (MIUR)
2013 - 2016
International Postdoctoral Fellowship within the INVEST (INternational VEnue for PoSTgraduate Education) Programme (COFUND) – 200,000 €
7th Framework EU Research Funding Programme (FP7)
Vita-Salute San Raffaele University, Milan (Italy)
2006 - 2010
Ph.D. Fellowship Recipient
FP6 Network of Excellence DC-THERA
Novartis Vaccines and Diagnostics, Siena (Italy)
PUBLICATIONS
1. Venzin, V.*, C. Beccaria*, C. Perucchini, P. Delfino, E. Bono, L. Giustini, F. Moalli, V. Fumagalli, M. Grillo, C. Laura, P. Di Lucia, K. Reinhard, J. Petschenka, T. Omokoko, S. Ottolini, A. Celant, K. Kawashima, M. Rava, M. De Giovanni, D. Inverso, M. Kuka, P. Kennedy, M. Guilliams, G. Casorati, U. Sahin, N. Le Bert, A. Bertoletti, F. Vascotto, L. G. Guidotti, F. Pedica, M. Ponzoni, and M. Iannacone. 2025. CD4+ T cells license Kupffer cells to reverse the CD8+ T cell dysfunction induced by hepatocellular priming. Nat Immunol
2. Sala, E.*, M. Nelli*, C. Laura, P. Di Lucia, C. G. Beccaria, E. B. Bono, M. Mangione, D. Marotta, V. Sperto, M. Grillo, L. Giustini, F. Tosi, J. Nie, D. Kim, G. Furiato, C. Malpighi, E. Consolo, B. Becher, E. David, M. Cohen, A. Giladi, I. Amit, R. Bosselut, L. G. Guidotti, M. Iannacone#, and M. Kuka#. 2025. T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses. EMBO J 44: 2400-2423.
3. Nelli, M., and M. Kuka#. 2024. The dual nature of TDC - bridging dendritic and T cells in immunity. FEBS Lett
4. Pallavicini, I., T. M. Frasconi, C. Catozzi, E. Ceccacci, S. Tiberti, D. Haas, J. Samson, C. Heuser-Loy, C. B. Nava Lauson, M. Mangione, E. Preto, A. Bigogno, E. Sala, M. Iannacone, C. Mercurio, L. Gattinoni, I. Caruana, M. Kuka, L. Nezi, S. Minucci, and T. Manzo. 2024. LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness. Nat Commun 15: 7366.
5. Fumagalli, V., M. Ravà, D. Marotta, P. Di Lucia, E. B. Bono, L. Giustini, F. De Leo, M. Casalgrandi, E. Monteleone, V. Mouro, C. Malpighi, C. Perucchini, M. Grillo, S. De Palma, L. Donnici, S. Marchese, M. Conti, H. Muramatsu, S. Perlman, N. Pardi, M. Kuka, R. De Francesco, M. E. Bianchi, L. G. Guidotti, and M. Iannacone. 2024. Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination. Nat Immunol.
6. Fiore, A., E. Sala, C. Laura, M. Riba, M. Nelli, V. Fumagalli, F. Oberrauch, M. Mangione, C. Cristofani, P. Provero, M. Iannacone, and M. Kuka#. 2023. A fluorescent reporter model for the visualization and characterization of TDC. Eur J Immunol e2350529.
7. Sandner, L., M. Alteneder, R. Rica, B. Woller, E. Sala, T. Frey, A. Tosevska, C. Zhu, M. Madern, M. Khan, P. Hoffmann, A. Schebesta, I. Taniuchi, M. Bonelli, K. Schmetterer, M. Iannacone, M. Kuka, W. Ellmeier, S. Sakaguchi, R. Herbst, and N. Boucheron. 2023. The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling. J Exp Med 220: e20221466.
8. Stoler-Barak, L., E. Harris, A. Peres, H. Hezroni, M. Kuka, P. Di Lucia, A. Grenov, N. Gurwicz, M. Kupervaser, B. H. Yip, M. Iannacone, G. Yaari, J. D. Crispino, and Z. Shulman. 2023. B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation. Nat Commun 14: 1462.
9. Fumagalli, V., V. Venzin, P. Di Lucia, F. Moalli, X. Ficht, G. Ambrosi, L. Giustini, F. Andreata, M. Grillo, D. Magini, M. Ravà, C. Friedrich, J. D. Fontenot, P. Bousso, S. A. Gilmore, S. Khan, M. Baca, E. Vivier, G. Gasteiger, M. Kuka, L. G. Guidotti, and M. Iannacone. 2022. Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability. Sci Immunol 7: eabi6112.
10. Fedeli, M., M. Kuka, A. Finardi, F. Albano, V. Viganò, M. Iannacone, R. Furlan, P. Dellabona, and G. Casorati. 2021. miR-21 sustains CD28 signalling and low-affinity T-cell responses at the expense of self-tolerance. Clin Transl Immunology 10: e1321.
11. Andreata, F., C. Blériot, P. Di Lucia, G. De Simone, V. Fumagalli, X. Ficht, C. G. Beccaria, M. Kuka, F. Ginhoux, and M. Iannacone. 2021. Isolation of mouse Kupffer cells for phenotypic and functional studies. STAR Protoc 2: 100831.
12. Kuka, M.#, and M. Iannacone#. 2021. Heterogeneity in antiviral B cell responses: Lessons from the movies. Immunol Rev
13. Conforti, A., E. Marra, F. Palombo, G. Roscilli, M. Ravà, V. Fumagalli, A. Muzi, M. Maffei, L. Luberto, L. Lione, E. Salvatori, M. Compagnone, E. Pinto, E. Pavoni, F. Bucci, G. Vitagliano, D. Stoppoloni, M. L. Pacello, M. Cappelletti, F. F. Ferrara, E. D’Acunto, V. Chiarini, R. Arriga, A. Nyska, P. Di Lucia, D. Marotta, E. Bono, L. Giustini, E. Sala, C. Perucchini, J. Paterson, K. A. Ryan, A. R. Challis, G. Matusali, F. Colavita, G. Caselli, E. Criscuolo, N. Clementi, N. Mancini, R. Groß, A. Seidel, L. Wettstein, J. Münch, L. Donnici, M. Conti, R. De Francesco, M. Kuka, G. Ciliberto, C. Castilletti, M. R. Capobianchi, G. Ippolito, L. G. Guidotti, L. Rovati, M. Iannacone, and L. Aurisicchio. 2021. COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19. Mol Ther
14. Fumagalli, V.*, M. Ravà*, D. Marotta*, P. Di Lucia, C. Laura, E. Sala, M. Grillo, E. Bono, L. Giustini, C. Perucchini, M. Mainetti, A. Sessa, J. M. Garcia-Manteiga, L. Donnici, L. Manganaro, S. Delbue, V. Broccoli, R. De Francesco, P. D’Adamo, M. Kuka, L. G. Guidotti, and M. Iannacone. 2021. Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion. Sci Immunol eabl9929.
15. Sala, E., and M. Kuka#. 2020. The Suppressive Attitude of Inflammatory Monocytes in Antiviral Antibody Responses. Viral Immunol 33: 327-333.
16. Fousteri, G.#, and M. Kuka#. 2020. The elusive identity of CXCR5+ CD8 T cells in viral infection and autoimmunity: Cytotoxic, regulatory, or helper cells. Mol Immunol 119: 101-105.
17. De Giovanni, M., V. Cutillo, A. Giladi, E. Sala, C. G. Maganuco, C. Medaglia, P. Di Lucia, E. Bono, C. Cristofani, E. Consolo, L. Giustini, A. Fiore, S. Eickhoff, W. Kastenmüller, I. Amit, M. Kuka#*, and M. Iannacone#*. 2020. Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells. Nat Immunol 21: 321-330.
18. Kuka, M., M. De Giovanni, and M. Iannacone. 2019. The role of type I interferons in CD4+ T cell differentiation. Immunol Lett 215: 19-23.
19. Bénéchet, A. P., G. De Simone, P. Di Lucia, F. Cilenti, G. Barbiera, N. Le Bert, V. Fumagalli, E. Lusito, F. Moalli, V. Bianchessi, F. Andreata, P. Zordan, E. Bono, L. Giustini, W. V. Bonilla, C. Bleriot, K. Kunasegaran, G. Gonzalez-Aseguinolaza, D. D. Pinschewer, P. T. F. Kennedy, L. Naldini, M. Kuka, F. Ginhoux, A. Cantore, A. Bertoletti, R. Ostuni, L. G. Guidotti, and M. Iannacone. 2019. Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming. Nature 574: 200-205.
20. De Simone, G., E. M. C. Mazza, A. Cassotta, A. N. Davydov, M. Kuka, V. Zanon, F. De Paoli, E. Scamardella, M. Metsger, A. Roberto, K. Pilipow, F. S. Colombo, E. Tenedini, E. Tagliafico, L. Gattinoni, D. Mavilio, C. Peano, D. A. Price, S. P. Singh, J. M. Farber, V. Serra, F. Cucca, F. Ferrari, V. Orrù, E. Fiorillo, M. Iannacone, D. M. Chudakov, F. Sallusto, and E. Lugli. 2019. CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential. J Immunol
21. Kuka, M., and M. Iannacone. 2018. Viral subversion of B cell responses within secondary lymphoid organs. Nat Rev Immunol 18: 255-265.
22. Jofra, T., R. Di Fonte, G. Galvani, M. Kuka, M. Iannacone, M. Battaglia, and G. Fousteri. 2018. Tr1 cell immunotherapy promotes transplant tolerance via de novo Tr1 cell induction in mice and is safe and effective during acute viral infection. Eur J Immunol
23. Thierry, G. R., M. Kuka, M. De Giovanni, I. Mondor, N. Brouilly, M. Iannacone, and M. Bajénoff. 2018. The conduit system exports locally secreted IgM from lymph nodes. J Exp Med 215: 2972-2983.
24. Sammicheli, S., M. Kuka, and M. Iannacone. 2018. Intravital Imaging of B Cell Responses in Lymph Nodes. Methods Mol Biol 1763: 63-74.
25. Kuka, M., and M. Iannacone. 2017. Intestinal Flossing Keeps Pathogens at Bay. Dev Cell 43: 383-384.
26. Jofra, T., G. Galvani, M. Kuka, R. Di Fonte, B. G. Mfarrej, M. Iannacone, S. Salek-Ardakani, M. Battaglia, and G. Fousteri. 2017. Extrinsic Protein Tyrosine Phosphatase Non-Receptor 22 Signals Contribute to CD8 T Cell Exhaustion and Promote Persistence of Chronic Lymphocytic Choriomeningitis Virus Infection. Front Immunol 8: 811.
27. Sammicheli, S., M. Kuka*, P. Di Lucia, N. J. de Oya, M. De Giovanni, J. Fioravanti, C. Cristofani, C. G. Maganuco, B. Fallet, L. Ganzer, L. Sironi, M. Mainetti, R. Ostuni, K. Larimore, P. D. Greenberg, J. C. de la Torre, L. G. Guidotti, and M. Iannacone. 2016. Inflammatory monocytes hinder antiviral B cell responses. Sci Immunol 1:
28. Fousteri, G., T. Jofra, R. Di Fonte, M. Kuka, M. Iannacone, and M. Battaglia. 2015. PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner. Clin Immunol 156: 98-108.
29. Kuka, M., and M. Iannacone. 2014. The role of lymph node sinus macrophages in host defense. Ann N Y Acad Sci 1319: 38-46.
30. Kuka, M.*, I. Munitic*, M. L. Giardino Torchia, and J. D. Ashwell. 2013. CD70 is downregulated by interaction with CD27. J Immunol 191: 2282-2289.
31. Munitic, I.*, M. Kuka*, A. Allam*, J. P. Scoville, and J. D. Ashwell. 2013. CD70 deficiency impairs effector CD8 T cell generation and viral clearance but is dispensable for the recall response to lymphocytic choriomeningitis virus. J Immunol 190: 1169-1179.
32. Kuka, M.#, and J. D. Ashwell#. 2013. A method for high purity sorting of rare cell subsets applied to TDC. J Immunol Methods 400-401: 111-116.
33. Kuka, M., I. Munitic, and J. D. Ashwell. 2012. Identification and characterization of polyclonal alphabeta-T cells with dendritic cell properties. Nat Commun 3: 1223.
34. Kuka, M., R. Baronio, S. Valentini, E. Monaci, A. Muzzi, S. Aprea, E. De Gregorio, and U. D’Oro. 2010. Src kinases are required for a balanced production of IL-12/IL-23 in human dendritic cells activated by Toll-like receptor agonists. PLoS One 5: e11491.
35. Rizzetto, L.*, M. Kuka*, C. De Filippo, A. Cambi, M. G. Netea, L. Beltrame, G. Napolitani, M. G. Torcia, U. D’Oro, and D. Cavalieri. 2010. Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism. J Immunol 184: 4258-4268.
36. Cavalieri, D., D. Rivero, L. Beltrame, S. I. Buschow, E. Calura, L. Rizzetto, S. Gessani, M. C. Gauzzi, W. Reith, A. Baur, R. Bonaiuti, M. Brandizi, C. De Filippo, U. D’Oro, S. Draghici, I. Dunand-Sauthier, E. Gatti, F. Granucci, M. Gundel, M. Kramer, M. Kuka, A. Lanyi, C. J. Melief, N. van Montfoort, R. Ostuni, P. Pierre, R. Popovici, E. Rajnavolgyi, S. Schierer, G. Schuler, V. Soumelis, A. Splendiani, I. Stefanini, M. G. Torcia, I. Zanoni, R. Zollinger, C. G. Figdor, and J. M. Austyn. 2010. DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells. Immunome Res 6: 10.
37. Casnici, C., G. Volpe, D. Lattuada, K. Crotta, M. Kuka, C. Panuzzo, C. Mastrotto, G. Tonon, V. M. Fazio, G. Saglio, and O. Marelli. 2009. Out of frame peptides from BCR/ABL alternative splicing are immunogenic in HLA A2.1 transgenic mice. Cancer Lett 276: 61-67.
38. Volpe, G., A. Cignetti, C. Panuzzo, M. Kuka, K. Vitaggio, M. Brancaccio, G. Perrone, M. Rinaldi, G. Prato, M. Fava, M. Geuna, M. Pautasso, C. Casnici, E. Signori, G. Tonon, G. Tarone, O. Marelli, V. M. Fazio, and G. Saglio. 2007. Alternative BCR/ABL splice variants in Philadelphia chromosome-positive leukemias result in novel tumor-specific fusion proteins that may represent potential targets for immunotherapy approaches. Cancer Res 67: 5300-5307.
* Equal contribution # Corresponding author
BIBLIOMETRIC INDICATORS
Total Peer-reviewed Publications: 38
H-index: 20 (Scopus), 21 (Google Scholar)
Original Research Articles: 26/38 First/co-first or last/co-last authorship: 18/38
Total impact factor: 444
Average impact factor: 11.7
AWARDS AND ACHIEVEMENTS
March 2022
AAI (American Association of Immunologists) Early Career Faculty Grant for the Immunology 2022 Meeting
Portland, Oregon (US)
July 2021
AAI (American Association of Immunologists) Registration Grant for the European Congress of Immunology 2021 (ECI2021)
March 2018
AAI (American Association of Immunologists) Trainee Abstract Award for the Immunology 2018 Meeting
Austin, Texas (US)
2018 – 2021
Member of the SIICA (Società di Immunologia, Immunologia Clinica e Allergologia) Junior Faculty
INVITED OR SELECTED TALKS
June 2026
Invited Speaker at the SIICA (Italian Society of Immunologists) National Meeting 2026
Brescia (Italy)
January 2026
Selected Speaker at the Von Boehmer Midwinter Conference 2026
Seefeld (Austria)
November 2025
Invited Speaker at the INF-ACT Annual Meeting 2025
Rome (Italy)
September 2024
Invited Speaker at the Satellite Symposium of the European Congress of Immunology (ECI) 2024
Dublin (Ireland)
April 2024
Selected Speaker at the Pathogen immunity and signalling (EMBO Workshop)
San Servolo, Venice (Italy)
February 2024
Invited Speaker at Univax Day 2024
Università Vita-Salute San Raffaele
January 2024
Selected Speaker at the Von Boehmer Midwinter Conference 2024
Seefeld (Austria)
December 2023
Invited Speaker at the LICB Branch Seminar, National Institutes of Health
Bethesda, Maryland (US)
December 2023
Invited Speaker at “Corso Residenziale Avanzato in Patologia e Clinica del Tratto Genitale Femminile Inferiore”
Milan (Italy)
May 2023
Selected Speaker at Immunology 2023 (AAI Annual Meeting)
Washington DC (US)
May 2022
Selected Speaker at Immunology 2022 (AAI Annual Meeting)
Portland, Oregon (US)
April 2022
Selected Speaker at the Pathogen immunity and signalling (EMBO Workshop)
Saint-Malo (France)
March 2021
Invited Speaker at Univax Day 2021
Online webinar (Italy) Università Vita-Salute San Raffaele
September 2020
Invited Speaker at Campus Orienta Digital 2.0
Online webinar (Italy) Università Vita-Salute San Raffaele
October 2019
Invited Speaker at SIAPEC-IAP Meeting (Congresso Triennale di Anatomia Patologica)
Turin (Italy)
June 2019
Invited Speaker at Single Cell Revolution 2.0 Meeting
Turin (Italy)
April 2019
Selected Speaker at Pathogen immunity and signalling (EMBO Workshop)
Oxford (UK)
May 2018
Selected Speaker at Immunology 2018 (AAI Annual Meeting)
Austin, Texas (US)
May 2017
Selected Speaker at Immunology 2017 (AAI Annual Meeting)
Washington, DC (US)
February 2017
Invited Speaker at the Advanced Immune Bio-Imaging Workshop
European Institute of Oncology, Milan (Italy)
November 2015
Invited Speaker at the 20th University of Rijeka Scientific Colloquium
University of Rijeka, Rijeka (Croatia)
September 2011
Selected Speaker at the NIH Immunology Retreat
Cambridge (Maryland, US)
October 2009 Invited Speaker at the SIICA Workshop "How advanced immunology can contribute to new vaccine generations"
Certosa di Pontignano, Siena (Italy)
MEETING ORGANIZATION
February 2025
UniVAX Day 2025
Università Vita-Salute San Raffaele
February 2024
UniVAX Day 2024
Università Vita-Salute San Raffaele
May 2022
Basic and Applied Immunology and Oncology (BAIO) PhD Workshop “Single cell-based Spatial OMICS approaches: from theory to recent applications in immunology and oncology”
San Raffaele Scientific Institute, Milan (Italy)
April 2022
Session Chair at the Pathogen immunity and signalling (EMBO Workshop)
Saint-Malo (France)
2020 - 2021
“Happy Hour with Immunology” live streaming events
Online webinar (Italy)
April-May 2020 The SIICA School of Immunology 2020 - VIRAL IMMUNOLOGY & VACCINOLOGY
Online webinar (Italy)
December 2019
SIICA International PhD Retreat
Camogli, Genova (Italy)
2018 - 2019
2019 DITID (Division of Immunology, Transplantation, and Infectious Diseases) Retreat
San Raffaele Scientific Institute, Milan (Italy)
July 2018
SIICA School of Immunology 2018
Messina (Italy)
2015 - 2016 6th MMI Meeting, February 2016
San Raffaele Scientific Institute, Milan (Italy)
2014 - 2015 5th MMI Meeting, February 2015
Fondazione Istituto Nazionale di Genetica Molecolare (INGM), Milan (Italy)
2013 - 2014 4th MMI Meeting, February 2014
Humanitas Research Hospital, Milan (Italy)
EDITORIAL ACTIVITY
2022 - Present
Review Editor
Frontiers in Immunology – Autoimmune and Autoinflammatory Disorders
2021 - Present
Associate Faculty Member
Faculty Opinions: London, GB
2020 - Present
Invited Reviewer for Cell Death & Disease, Science Immunology, Cellular & Molecular Immunology, European Journal of Immunology, Frontiers in Immunology
2018 - Present
Review Editor
Frontiers in Immunology – Viral Immunology
2015 - Present Review Editor
Frontiers in Immunology – Molecular Innate Immunity
GRANT REVIEWING
2023 - Present Projects submitted to the Grands Programmes de recherche de l’Université PSL (2025-2029)/PSL University’s Major Research Programs (2025-2029), the Swiss National Science Foundation, and the French National Research Agency (ANR).
TEACHING ACTIVITY
Academic Years
2016 – 2026
Patologia generale e Immunologia
(Coordinator Prof. Guido Poli)
Corso di Laurea in Ricerca biotecnologica in medicina – CLRMBM
Academic Years
2016 – 2025
Basic Pathology and Immunology
(Coordinator Prof. Guido Poli)
International MD Program Corso di Laurea Magistrale in Medicina e Chirurgia - CLMMCI)
Academic Years
2017 – 2025
Patologia
(Coordinator Prof. Ruggero Pardi and Prof. Luca Guidotti)
Corso di Laurea magistrale in Medicina e Chirurgia - CLMMC
Academic Years 2017 – 2026
Patologia
(Coordinator Prof. Luca G. Guidotti and Prof. Matteo Iannacone)
Corso di Laurea Magistrale in Odontoiatria e Protesi Dentaria - CLMOPD
Academic Years 2017 – 2019
Patologia generale di interesse infermieristico
(Coordinator Prof. Patrizia Rovere Querini)
Corso di Laurea in Infermieristica
PAST INSTITUTIONAL ACTIVITY
2021 – 2024
Board Member of the PhD Curriculum in Basic and Applied Immunology and Oncology
International PhD Program in Molecular Medicine
Vita-Salute San Raffaele University (Milan, Italy)
2020 – 2024
Member of the OSR Institutional Seminars Organizing Committee
San Raffaele Scientific Institute (Milan, Italy)
2020 – 2024
Member of the DITID Divisional Seminars Organizing Committee
San Raffaele Scientific Institute, Milan (Italy)
MENTORING ACTIVITY
October 2015 - present Mentor and Official Supervisor of 11 undergraduate students
November 2016 - present Mentor and Official Supervisor of 7 predoctoral research fellows
November 2018 - present Mentor and Official Director of Studies of 3 PhD students
May 2022 - present Mentor and Official Supervisor of 2 postdoctoral fellows
RESEARCH INTERRUPTIONS
April 2016 – September 2016: Maternity Leave
December 2019 – August 2020: Maternity Leave
2024 - Present Associate Professor of Pathology (MEDS-02/A)
School of Medicine
Vita-Salute San Raffaele University, Milan (Italy)
2025 - 2037 National Scientific Qualification (ASN)
Full Professor of Pathology (MEDS-02/A)
2023 - Present Project Leader
Division of Immunology, Transplantation and Infectious Diseases
San Raffaele Scientific Institute, Milan (Italy)
INSTITUTIONAL RESPONSABILITIES
2025 – Present
Vice President of the Bachelor’s Degree in Biotechnology Research in Medicine
Vita-Salute San Raffaele University (Milan, Italy)
2024 – Present
Coordinator of the PhD Curriculum in Basic and Applied Immunology and Oncology
International PhD Program in Molecular Medicine
Vita-Salute San Raffaele University (Milan, Italy)
PAST WORK EXPERIENCE
2021 - 2024 Assistant Professor of Pathology (RTDB MED/04)
2016 - 2021 Researcher and Lecturer of Pathology (RTDA MED/04)
School of Medicine
Vita-Salute San Raffaele University, Milan (Italy)
2016 - 2023 Young Principal Investigator
2013 - 2016
Senior Postdoctoral Fellow
Dynamics of Immune Responses Unit (Head Prof. Matteo Iannacone)
Division of Immunology, Transplantation and Infectious Diseases
San Raffaele Scientific Institute, Milan (Italy)
2010 - 2013 Postdoctoral Fellow
Laboratory of Immune Cell Biology (Head Dr. Jonathan D. Ashwell)
National Cancer Institute (NCI)
National Institutes of Health, Bethesda (Maryland, US)
2006 - 2010
Ph.D Student/Research Fellow
Adjuvants Team (Head Dr. Ugo D’Oro)
Department of Immunology
Novartis Vaccines and Diagnostics, Siena (Italy)
Collaborative Ph.D. program between University of Siena, Novartis Vaccines and Diagnostics, and the FP6 Network of Excellence DC-THERA
2003 - 2006
Undergraduate Student (Bachelor and Master Thesis)
Department of Clinical and Biological Sciences (Supervisor Prof. Giuseppe Saglio)
University of Turin, San Luigi Hospital, Orbassano (Italy)
2003
Undergraduate Student (Internship)
Department of Genetics, Biology and Biochemistry (Supervisor Prof. Mara Brancaccio)
University of Turin, Turin (Italy)
EDUCATION
January 2010
Ph.D. in Cellular and Molecular Biology
School of Evolutionary Biology
University of Siena, Siena (Italy)
July 2006
Master of Science in Molecular Biotechnologies (110/110 cum laude)
University of Turin, Turin (Italy)
July 2004
Bachelor of Science in Biotechnologies (110/110 cum laude)
University of Turin Turin (Italy)
FUNDING
2025 – 2030
AIRC Investigator Grant – 1,200,000 € (PI)
Italian Ministry of University and Research (MUR)
2023 – 2027
Ricerca finalizzata 2021 (Young Researchers) – 225,000 € (Operative Unit PI)
Italian Ministry of Health
2023 – 2025
PRIN 2022 PNRR – 120,000 € (PI)
Italian Ministry of University and Research (MUR)
2022 – 2025
PNRR INF-ACT – Member of the UniSR Team - Spoke 1
Vita-Salute San Raffaele University, Milan (Italy)
2023 – 2024
Research contract (Assegno di ricerca) sponsored by UniSR for the recruitment of a young fellow – 24,000 € (PI)
Vita-Salute San Raffaele University, Milan (Italy)
2022 – 2025
PRIN 2020 – 172,000 € (Local Unit PI)
Italian Ministry of University and Research (MUR)
2019 – 2023
PRIN 2017 – 407,000 € (Local Unit PI)
Italian Ministry of Education, University, and Research (MIUR)
2015 – 2020
Scientific Independence of Young Researchers (SIR) – 539,000 € (PI)
Italian Ministry of Education, University, and Research (MIUR)
2013 - 2016
International Postdoctoral Fellowship within the INVEST (INternational VEnue for PoSTgraduate Education) Programme (COFUND) – 200,000 €
7th Framework EU Research Funding Programme (FP7)
Vita-Salute San Raffaele University, Milan (Italy)
2006 - 2010
Ph.D. Fellowship Recipient
FP6 Network of Excellence DC-THERA
Novartis Vaccines and Diagnostics, Siena (Italy)
PUBLICATIONS
1. Venzin, V.*, C. Beccaria*, C. Perucchini, P. Delfino, E. Bono, L. Giustini, F. Moalli, V. Fumagalli, M. Grillo, C. Laura, P. Di Lucia, K. Reinhard, J. Petschenka, T. Omokoko, S. Ottolini, A. Celant, K. Kawashima, M. Rava, M. De Giovanni, D. Inverso, M. Kuka, P. Kennedy, M. Guilliams, G. Casorati, U. Sahin, N. Le Bert, A. Bertoletti, F. Vascotto, L. G. Guidotti, F. Pedica, M. Ponzoni, and M. Iannacone. 2025. CD4+ T cells license Kupffer cells to reverse the CD8+ T cell dysfunction induced by hepatocellular priming. Nat Immunol
2. Sala, E.*, M. Nelli*, C. Laura, P. Di Lucia, C. G. Beccaria, E. B. Bono, M. Mangione, D. Marotta, V. Sperto, M. Grillo, L. Giustini, F. Tosi, J. Nie, D. Kim, G. Furiato, C. Malpighi, E. Consolo, B. Becher, E. David, M. Cohen, A. Giladi, I. Amit, R. Bosselut, L. G. Guidotti, M. Iannacone#, and M. Kuka#. 2025. T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses. EMBO J 44: 2400-2423.
3. Nelli, M., and M. Kuka#. 2024. The dual nature of TDC - bridging dendritic and T cells in immunity. FEBS Lett
4. Pallavicini, I., T. M. Frasconi, C. Catozzi, E. Ceccacci, S. Tiberti, D. Haas, J. Samson, C. Heuser-Loy, C. B. Nava Lauson, M. Mangione, E. Preto, A. Bigogno, E. Sala, M. Iannacone, C. Mercurio, L. Gattinoni, I. Caruana, M. Kuka, L. Nezi, S. Minucci, and T. Manzo. 2024. LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness. Nat Commun 15: 7366.
5. Fumagalli, V., M. Ravà, D. Marotta, P. Di Lucia, E. B. Bono, L. Giustini, F. De Leo, M. Casalgrandi, E. Monteleone, V. Mouro, C. Malpighi, C. Perucchini, M. Grillo, S. De Palma, L. Donnici, S. Marchese, M. Conti, H. Muramatsu, S. Perlman, N. Pardi, M. Kuka, R. De Francesco, M. E. Bianchi, L. G. Guidotti, and M. Iannacone. 2024. Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination. Nat Immunol.
6. Fiore, A., E. Sala, C. Laura, M. Riba, M. Nelli, V. Fumagalli, F. Oberrauch, M. Mangione, C. Cristofani, P. Provero, M. Iannacone, and M. Kuka#. 2023. A fluorescent reporter model for the visualization and characterization of TDC. Eur J Immunol e2350529.
7. Sandner, L., M. Alteneder, R. Rica, B. Woller, E. Sala, T. Frey, A. Tosevska, C. Zhu, M. Madern, M. Khan, P. Hoffmann, A. Schebesta, I. Taniuchi, M. Bonelli, K. Schmetterer, M. Iannacone, M. Kuka, W. Ellmeier, S. Sakaguchi, R. Herbst, and N. Boucheron. 2023. The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling. J Exp Med 220: e20221466.
8. Stoler-Barak, L., E. Harris, A. Peres, H. Hezroni, M. Kuka, P. Di Lucia, A. Grenov, N. Gurwicz, M. Kupervaser, B. H. Yip, M. Iannacone, G. Yaari, J. D. Crispino, and Z. Shulman. 2023. B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation. Nat Commun 14: 1462.
9. Fumagalli, V., V. Venzin, P. Di Lucia, F. Moalli, X. Ficht, G. Ambrosi, L. Giustini, F. Andreata, M. Grillo, D. Magini, M. Ravà, C. Friedrich, J. D. Fontenot, P. Bousso, S. A. Gilmore, S. Khan, M. Baca, E. Vivier, G. Gasteiger, M. Kuka, L. G. Guidotti, and M. Iannacone. 2022. Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability. Sci Immunol 7: eabi6112.
10. Fedeli, M., M. Kuka, A. Finardi, F. Albano, V. Viganò, M. Iannacone, R. Furlan, P. Dellabona, and G. Casorati. 2021. miR-21 sustains CD28 signalling and low-affinity T-cell responses at the expense of self-tolerance. Clin Transl Immunology 10: e1321.
11. Andreata, F., C. Blériot, P. Di Lucia, G. De Simone, V. Fumagalli, X. Ficht, C. G. Beccaria, M. Kuka, F. Ginhoux, and M. Iannacone. 2021. Isolation of mouse Kupffer cells for phenotypic and functional studies. STAR Protoc 2: 100831.
12. Kuka, M.#, and M. Iannacone#. 2021. Heterogeneity in antiviral B cell responses: Lessons from the movies. Immunol Rev
13. Conforti, A., E. Marra, F. Palombo, G. Roscilli, M. Ravà, V. Fumagalli, A. Muzi, M. Maffei, L. Luberto, L. Lione, E. Salvatori, M. Compagnone, E. Pinto, E. Pavoni, F. Bucci, G. Vitagliano, D. Stoppoloni, M. L. Pacello, M. Cappelletti, F. F. Ferrara, E. D’Acunto, V. Chiarini, R. Arriga, A. Nyska, P. Di Lucia, D. Marotta, E. Bono, L. Giustini, E. Sala, C. Perucchini, J. Paterson, K. A. Ryan, A. R. Challis, G. Matusali, F. Colavita, G. Caselli, E. Criscuolo, N. Clementi, N. Mancini, R. Groß, A. Seidel, L. Wettstein, J. Münch, L. Donnici, M. Conti, R. De Francesco, M. Kuka, G. Ciliberto, C. Castilletti, M. R. Capobianchi, G. Ippolito, L. G. Guidotti, L. Rovati, M. Iannacone, and L. Aurisicchio. 2021. COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19. Mol Ther
14. Fumagalli, V.*, M. Ravà*, D. Marotta*, P. Di Lucia, C. Laura, E. Sala, M. Grillo, E. Bono, L. Giustini, C. Perucchini, M. Mainetti, A. Sessa, J. M. Garcia-Manteiga, L. Donnici, L. Manganaro, S. Delbue, V. Broccoli, R. De Francesco, P. D’Adamo, M. Kuka, L. G. Guidotti, and M. Iannacone. 2021. Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion. Sci Immunol eabl9929.
15. Sala, E., and M. Kuka#. 2020. The Suppressive Attitude of Inflammatory Monocytes in Antiviral Antibody Responses. Viral Immunol 33: 327-333.
16. Fousteri, G.#, and M. Kuka#. 2020. The elusive identity of CXCR5+ CD8 T cells in viral infection and autoimmunity: Cytotoxic, regulatory, or helper cells. Mol Immunol 119: 101-105.
17. De Giovanni, M., V. Cutillo, A. Giladi, E. Sala, C. G. Maganuco, C. Medaglia, P. Di Lucia, E. Bono, C. Cristofani, E. Consolo, L. Giustini, A. Fiore, S. Eickhoff, W. Kastenmüller, I. Amit, M. Kuka#*, and M. Iannacone#*. 2020. Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells. Nat Immunol 21: 321-330.
18. Kuka, M., M. De Giovanni, and M. Iannacone. 2019. The role of type I interferons in CD4+ T cell differentiation. Immunol Lett 215: 19-23.
19. Bénéchet, A. P., G. De Simone, P. Di Lucia, F. Cilenti, G. Barbiera, N. Le Bert, V. Fumagalli, E. Lusito, F. Moalli, V. Bianchessi, F. Andreata, P. Zordan, E. Bono, L. Giustini, W. V. Bonilla, C. Bleriot, K. Kunasegaran, G. Gonzalez-Aseguinolaza, D. D. Pinschewer, P. T. F. Kennedy, L. Naldini, M. Kuka, F. Ginhoux, A. Cantore, A. Bertoletti, R. Ostuni, L. G. Guidotti, and M. Iannacone. 2019. Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming. Nature 574: 200-205.
20. De Simone, G., E. M. C. Mazza, A. Cassotta, A. N. Davydov, M. Kuka, V. Zanon, F. De Paoli, E. Scamardella, M. Metsger, A. Roberto, K. Pilipow, F. S. Colombo, E. Tenedini, E. Tagliafico, L. Gattinoni, D. Mavilio, C. Peano, D. A. Price, S. P. Singh, J. M. Farber, V. Serra, F. Cucca, F. Ferrari, V. Orrù, E. Fiorillo, M. Iannacone, D. M. Chudakov, F. Sallusto, and E. Lugli. 2019. CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential. J Immunol
21. Kuka, M., and M. Iannacone. 2018. Viral subversion of B cell responses within secondary lymphoid organs. Nat Rev Immunol 18: 255-265.
22. Jofra, T., R. Di Fonte, G. Galvani, M. Kuka, M. Iannacone, M. Battaglia, and G. Fousteri. 2018. Tr1 cell immunotherapy promotes transplant tolerance via de novo Tr1 cell induction in mice and is safe and effective during acute viral infection. Eur J Immunol
23. Thierry, G. R., M. Kuka, M. De Giovanni, I. Mondor, N. Brouilly, M. Iannacone, and M. Bajénoff. 2018. The conduit system exports locally secreted IgM from lymph nodes. J Exp Med 215: 2972-2983.
24. Sammicheli, S., M. Kuka, and M. Iannacone. 2018. Intravital Imaging of B Cell Responses in Lymph Nodes. Methods Mol Biol 1763: 63-74.
25. Kuka, M., and M. Iannacone. 2017. Intestinal Flossing Keeps Pathogens at Bay. Dev Cell 43: 383-384.
26. Jofra, T., G. Galvani, M. Kuka, R. Di Fonte, B. G. Mfarrej, M. Iannacone, S. Salek-Ardakani, M. Battaglia, and G. Fousteri. 2017. Extrinsic Protein Tyrosine Phosphatase Non-Receptor 22 Signals Contribute to CD8 T Cell Exhaustion and Promote Persistence of Chronic Lymphocytic Choriomeningitis Virus Infection. Front Immunol 8: 811.
27. Sammicheli, S., M. Kuka*, P. Di Lucia, N. J. de Oya, M. De Giovanni, J. Fioravanti, C. Cristofani, C. G. Maganuco, B. Fallet, L. Ganzer, L. Sironi, M. Mainetti, R. Ostuni, K. Larimore, P. D. Greenberg, J. C. de la Torre, L. G. Guidotti, and M. Iannacone. 2016. Inflammatory monocytes hinder antiviral B cell responses. Sci Immunol 1:
28. Fousteri, G., T. Jofra, R. Di Fonte, M. Kuka, M. Iannacone, and M. Battaglia. 2015. PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner. Clin Immunol 156: 98-108.
29. Kuka, M., and M. Iannacone. 2014. The role of lymph node sinus macrophages in host defense. Ann N Y Acad Sci 1319: 38-46.
30. Kuka, M.*, I. Munitic*, M. L. Giardino Torchia, and J. D. Ashwell. 2013. CD70 is downregulated by interaction with CD27. J Immunol 191: 2282-2289.
31. Munitic, I.*, M. Kuka*, A. Allam*, J. P. Scoville, and J. D. Ashwell. 2013. CD70 deficiency impairs effector CD8 T cell generation and viral clearance but is dispensable for the recall response to lymphocytic choriomeningitis virus. J Immunol 190: 1169-1179.
32. Kuka, M.#, and J. D. Ashwell#. 2013. A method for high purity sorting of rare cell subsets applied to TDC. J Immunol Methods 400-401: 111-116.
33. Kuka, M., I. Munitic, and J. D. Ashwell. 2012. Identification and characterization of polyclonal alphabeta-T cells with dendritic cell properties. Nat Commun 3: 1223.
34. Kuka, M., R. Baronio, S. Valentini, E. Monaci, A. Muzzi, S. Aprea, E. De Gregorio, and U. D’Oro. 2010. Src kinases are required for a balanced production of IL-12/IL-23 in human dendritic cells activated by Toll-like receptor agonists. PLoS One 5: e11491.
35. Rizzetto, L.*, M. Kuka*, C. De Filippo, A. Cambi, M. G. Netea, L. Beltrame, G. Napolitani, M. G. Torcia, U. D’Oro, and D. Cavalieri. 2010. Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism. J Immunol 184: 4258-4268.
36. Cavalieri, D., D. Rivero, L. Beltrame, S. I. Buschow, E. Calura, L. Rizzetto, S. Gessani, M. C. Gauzzi, W. Reith, A. Baur, R. Bonaiuti, M. Brandizi, C. De Filippo, U. D’Oro, S. Draghici, I. Dunand-Sauthier, E. Gatti, F. Granucci, M. Gundel, M. Kramer, M. Kuka, A. Lanyi, C. J. Melief, N. van Montfoort, R. Ostuni, P. Pierre, R. Popovici, E. Rajnavolgyi, S. Schierer, G. Schuler, V. Soumelis, A. Splendiani, I. Stefanini, M. G. Torcia, I. Zanoni, R. Zollinger, C. G. Figdor, and J. M. Austyn. 2010. DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells. Immunome Res 6: 10.
37. Casnici, C., G. Volpe, D. Lattuada, K. Crotta, M. Kuka, C. Panuzzo, C. Mastrotto, G. Tonon, V. M. Fazio, G. Saglio, and O. Marelli. 2009. Out of frame peptides from BCR/ABL alternative splicing are immunogenic in HLA A2.1 transgenic mice. Cancer Lett 276: 61-67.
38. Volpe, G., A. Cignetti, C. Panuzzo, M. Kuka, K. Vitaggio, M. Brancaccio, G. Perrone, M. Rinaldi, G. Prato, M. Fava, M. Geuna, M. Pautasso, C. Casnici, E. Signori, G. Tonon, G. Tarone, O. Marelli, V. M. Fazio, and G. Saglio. 2007. Alternative BCR/ABL splice variants in Philadelphia chromosome-positive leukemias result in novel tumor-specific fusion proteins that may represent potential targets for immunotherapy approaches. Cancer Res 67: 5300-5307.
* Equal contribution # Corresponding author
BIBLIOMETRIC INDICATORS
Total Peer-reviewed Publications: 38
H-index: 20 (Scopus), 21 (Google Scholar)
Original Research Articles: 26/38 First/co-first or last/co-last authorship: 18/38
Total impact factor: 444
Average impact factor: 11.7
AWARDS AND ACHIEVEMENTS
March 2022
AAI (American Association of Immunologists) Early Career Faculty Grant for the Immunology 2022 Meeting
Portland, Oregon (US)
July 2021
AAI (American Association of Immunologists) Registration Grant for the European Congress of Immunology 2021 (ECI2021)
March 2018
AAI (American Association of Immunologists) Trainee Abstract Award for the Immunology 2018 Meeting
Austin, Texas (US)
2018 – 2021
Member of the SIICA (Società di Immunologia, Immunologia Clinica e Allergologia) Junior Faculty
INVITED OR SELECTED TALKS
June 2026
Invited Speaker at the SIICA (Italian Society of Immunologists) National Meeting 2026
Brescia (Italy)
January 2026
Selected Speaker at the Von Boehmer Midwinter Conference 2026
Seefeld (Austria)
November 2025
Invited Speaker at the INF-ACT Annual Meeting 2025
Rome (Italy)
September 2024
Invited Speaker at the Satellite Symposium of the European Congress of Immunology (ECI) 2024
Dublin (Ireland)
April 2024
Selected Speaker at the Pathogen immunity and signalling (EMBO Workshop)
San Servolo, Venice (Italy)
February 2024
Invited Speaker at Univax Day 2024
Università Vita-Salute San Raffaele
January 2024
Selected Speaker at the Von Boehmer Midwinter Conference 2024
Seefeld (Austria)
December 2023
Invited Speaker at the LICB Branch Seminar, National Institutes of Health
Bethesda, Maryland (US)
December 2023
Invited Speaker at “Corso Residenziale Avanzato in Patologia e Clinica del Tratto Genitale Femminile Inferiore”
Milan (Italy)
May 2023
Selected Speaker at Immunology 2023 (AAI Annual Meeting)
Washington DC (US)
May 2022
Selected Speaker at Immunology 2022 (AAI Annual Meeting)
Portland, Oregon (US)
April 2022
Selected Speaker at the Pathogen immunity and signalling (EMBO Workshop)
Saint-Malo (France)
March 2021
Invited Speaker at Univax Day 2021
Online webinar (Italy) Università Vita-Salute San Raffaele
September 2020
Invited Speaker at Campus Orienta Digital 2.0
Online webinar (Italy) Università Vita-Salute San Raffaele
October 2019
Invited Speaker at SIAPEC-IAP Meeting (Congresso Triennale di Anatomia Patologica)
Turin (Italy)
June 2019
Invited Speaker at Single Cell Revolution 2.0 Meeting
Turin (Italy)
April 2019
Selected Speaker at Pathogen immunity and signalling (EMBO Workshop)
Oxford (UK)
May 2018
Selected Speaker at Immunology 2018 (AAI Annual Meeting)
Austin, Texas (US)
May 2017
Selected Speaker at Immunology 2017 (AAI Annual Meeting)
Washington, DC (US)
February 2017
Invited Speaker at the Advanced Immune Bio-Imaging Workshop
European Institute of Oncology, Milan (Italy)
November 2015
Invited Speaker at the 20th University of Rijeka Scientific Colloquium
University of Rijeka, Rijeka (Croatia)
September 2011
Selected Speaker at the NIH Immunology Retreat
Cambridge (Maryland, US)
October 2009 Invited Speaker at the SIICA Workshop "How advanced immunology can contribute to new vaccine generations"
Certosa di Pontignano, Siena (Italy)
MEETING ORGANIZATION
February 2025
UniVAX Day 2025
Università Vita-Salute San Raffaele
February 2024
UniVAX Day 2024
Università Vita-Salute San Raffaele
May 2022
Basic and Applied Immunology and Oncology (BAIO) PhD Workshop “Single cell-based Spatial OMICS approaches: from theory to recent applications in immunology and oncology”
San Raffaele Scientific Institute, Milan (Italy)
April 2022
Session Chair at the Pathogen immunity and signalling (EMBO Workshop)
Saint-Malo (France)
2020 - 2021
“Happy Hour with Immunology” live streaming events
Online webinar (Italy)
April-May 2020 The SIICA School of Immunology 2020 - VIRAL IMMUNOLOGY & VACCINOLOGY
Online webinar (Italy)
December 2019
SIICA International PhD Retreat
Camogli, Genova (Italy)
2018 - 2019
2019 DITID (Division of Immunology, Transplantation, and Infectious Diseases) Retreat
San Raffaele Scientific Institute, Milan (Italy)
July 2018
SIICA School of Immunology 2018
Messina (Italy)
2015 - 2016 6th MMI Meeting, February 2016
San Raffaele Scientific Institute, Milan (Italy)
2014 - 2015 5th MMI Meeting, February 2015
Fondazione Istituto Nazionale di Genetica Molecolare (INGM), Milan (Italy)
2013 - 2014 4th MMI Meeting, February 2014
Humanitas Research Hospital, Milan (Italy)
EDITORIAL ACTIVITY
2022 - Present
Review Editor
Frontiers in Immunology – Autoimmune and Autoinflammatory Disorders
2021 - Present
Associate Faculty Member
Faculty Opinions: London, GB
2020 - Present
Invited Reviewer for Cell Death & Disease, Science Immunology, Cellular & Molecular Immunology, European Journal of Immunology, Frontiers in Immunology
2018 - Present
Review Editor
Frontiers in Immunology – Viral Immunology
2015 - Present Review Editor
Frontiers in Immunology – Molecular Innate Immunity
GRANT REVIEWING
2023 - Present Projects submitted to the Grands Programmes de recherche de l’Université PSL (2025-2029)/PSL University’s Major Research Programs (2025-2029), the Swiss National Science Foundation, and the French National Research Agency (ANR).
TEACHING ACTIVITY
Academic Years
2016 – 2026
Patologia generale e Immunologia
(Coordinator Prof. Guido Poli)
Corso di Laurea in Ricerca biotecnologica in medicina – CLRMBM
Academic Years
2016 – 2025
Basic Pathology and Immunology
(Coordinator Prof. Guido Poli)
International MD Program Corso di Laurea Magistrale in Medicina e Chirurgia - CLMMCI)
Academic Years
2017 – 2025
Patologia
(Coordinator Prof. Ruggero Pardi and Prof. Luca Guidotti)
Corso di Laurea magistrale in Medicina e Chirurgia - CLMMC
Academic Years 2017 – 2026
Patologia
(Coordinator Prof. Luca G. Guidotti and Prof. Matteo Iannacone)
Corso di Laurea Magistrale in Odontoiatria e Protesi Dentaria - CLMOPD
Academic Years 2017 – 2019
Patologia generale di interesse infermieristico
(Coordinator Prof. Patrizia Rovere Querini)
Corso di Laurea in Infermieristica
PAST INSTITUTIONAL ACTIVITY
2021 – 2024
Board Member of the PhD Curriculum in Basic and Applied Immunology and Oncology
International PhD Program in Molecular Medicine
Vita-Salute San Raffaele University (Milan, Italy)
2020 – 2024
Member of the OSR Institutional Seminars Organizing Committee
San Raffaele Scientific Institute (Milan, Italy)
2020 – 2024
Member of the DITID Divisional Seminars Organizing Committee
San Raffaele Scientific Institute, Milan (Italy)
MENTORING ACTIVITY
October 2015 - present Mentor and Official Supervisor of 11 undergraduate students
November 2016 - present Mentor and Official Supervisor of 7 predoctoral research fellows
November 2018 - present Mentor and Official Director of Studies of 3 PhD students
May 2022 - present Mentor and Official Supervisor of 2 postdoctoral fellows
RESEARCH INTERRUPTIONS
April 2016 – September 2016: Maternity Leave
December 2019 – August 2020: Maternity Leave
Concepts (10)
Publications (38)
Courses (23)
13 CFU
163 hours
9.6 CFU
126 hours
9.6 CFU
126 hours
9.6 CFU
126 hours
9.6 CFU
126 hours
9.6 CFU
126 hours
9.6 CFU
126 hours
9.6 CFU
126 hours
9.6 CFU
126 hours
.8 CFU
11 hours
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11 hours
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11 hours
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11 hours
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11 hours
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11 hours
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11 hours
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11 hours
8 CFU
96 hours
5 CFU
60 hours
7 CFU
60 hours
1 CFU
10 hours
7 CFU
79 hours
3 CFU
30 hours
No Results Found
Awards and honors (9)
AIRC Investigator Grant,
conferred by Associaciazione Italiana per la Ricerca sul Cancro - 2025
PRIN 2022 PNRR,
conferred by MUR - Unione Europea - 2023
Ricerca finalizzata 2021 (GR),
conferred by Ministero della Salute - 2022
Early Career Faculty Grant,
conferred by AAI (American Association of Immunologists) - 2022
PRIN2020 (Coordinator of local Research Unit),
conferred by MUR - 2021
PRIN2017 (Coordinator of local Research Unit),
conferred by MIUR - 2019
COFUND - Marie Curie Incoming Fellowship,
conferred by European commission - Académie de Louvain - 2013
DC-Thera European Network Ph.D. Fellowship,
conferred by European Union - 2006
No Results Found
Fellowship (4)
fs2 – Socio/a effettivo o corrispondente
- NIBIT Network Italiano per la Bioterapia dei Tumori (Italia)
(2022 - )
2022
Componente del Comitato Scientifico
- SIICA Junior Faculty (Italia)
(2018 - 2021)
2018
fs2 – Socio/a effettivo o corrispondente
- SIICA (Italia)
(2018 - )
2018
fs2 – Socio/a effettivo o corrispondente
- AAI (Stati Uniti)
(2017 - )
2017
No Results Found
Editorial Board (2)
Associate Editor di rivista o collana editoriale - Faculty Opinions: London, GBAssociate Faculty Member (2021 - )
2021
Editor di rivista, collana editoriale, enciclopedia - FRONTIERS IN IMMUNOLOGY - ISSN: 1664-3224 - Lausanne : Frontiers Research Foundation, 2010- (2015 - )
2015
No Results Found
Research and teaching at institutions (5)
Position carried out at: UNISR - Università Vita Salute San Raffaele - Ricercatore/Ricercatrice universitario a t.d.
(04/06/2024 - 15/08/2024)20240604
Position carried out at: UNISR - Università Vita Salute San Raffaele - Ricercatore/Ricercatrice universitario a t.d.
(16/08/2021 - 03/06/2024)20210816
Position carried out at: UNISR - Università Vita Salute San Raffaele - Ricercatore/Ricercatrice universitario a t.d.
(16/03/2016 - 15/08/2021)20160316
Position carried out at: University of Rijeka - Attivita' di insegnamento
(09/11/2015 - 11/11/2015)20151109
Postdoctoral Fellow at: National Institutes of Health - Ricercatore/Ricercatrice all’estero
(15/03/2010 - 03/06/2013)20100315
No Results Found
Congresses (5)
Program committee (membro del comitato scientifico) - The SIICA School of Immunology 2020 - VIRAL IMMUNOLOGY & VACCINOLOGY (02/05/2025 - ) 20250502
Program committee (membro del comitato scientifico) - UniVAX Day 2025 (05/02/2025 - ) 20250205
Program committee (membro del comitato scientifico) - UniVAX Day 2024 (07/02/2024 - ) 20240207
Program committee (membro del comitato scientifico) - SIICA International PhD Retreat (04/12/2019 - ) 20191204
Program committee (membro del comitato scientifico) - SIICA School of Immunology 2018 (20/07/2018 - ) 20180720
No Results Found
Third Mission (4)
Attività di coinvolgimento e interazione con il mondo della scuola (Organizzatore/Organizzatrice, Relatore/Relatrice)
- UniVAX Day 2025
Università Vita-Salute San Raffaele, Via Olgettina 58, Milano (05/02/2025 - 05/02/2025) 20250205
Facoltà di Medicina e Chirurgia
Attività di coinvolgimento e interazione con il mondo della scuola (Organizzatore/Organizzatrice)
- UniVax Day 2024
Università Vita-Salute San Raffaele (07/02/2024 - ) 20240207
Facoltà di Medicina e Chirurgia
Pubblicazioni (cartacee e digitali) dedicate al pubblico non accademico (Responsabile scientifico)
- Intervista per Il Corriere della Sera
19000101
Facoltà di Medicina e Chirurgia
Pubblicazioni (cartacee e digitali) dedicate al pubblico non accademico (Responsabile scientifico)
- Intervista per Innlifes (Innovation in Life Science)
19000101
Facoltà di Medicina e Chirurgia
No Results Found