PSMA PET in brain metastases: navigating diagnostic challenges– a thorough exploration

PSMA imaging is gaining importance in the field of oncology, both for diagnostic and therapeutic purposes. In this review, we aimed to highlight the significance of detecting brain metastases from prostate carcinoma before the onset of symptoms, also considering potential pitfalls and false-positive findings. To emphasize this aspect, we present a case report in which the use of an extended field of view to the vertex allowed to the localization of brain lesions before the onset of symptoms. The present clinical report describe the rare case of brain metastases from prostate carcinoma detected by [18F]F-PSMA-1007 PET/CT.