Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial
Articolo
Data di Pubblicazione:
2022
Citazione:
Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial / Lewis, Gregory D; Voors, Adriaan A; Cohen-Solal, Alain; Metra, Marco; Whellan, David J; Ezekowitz, Justin A; Böhm, Michael; Teerlink, John R; Docherty, Kieran F; Lopes, Renato D; Divanji, Punag H; Heitner, Stephen B; Kupfer, Stuart; Malik, Fady I; Meng, Lisa; Wohltman, Amy; Felker, G Michael. - In: JAMA. - ISSN 0098-7484. - 328:3(2022), pp. 259-269. [10.1001/jama.2022.11016]
Abstract:
Exercise limitation is a cardinal manifestation of heart failure with reduced ejection fraction (HFrEF) but is not consistently improved by any of the current guideline-directed medical therapies.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Aged; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Ventricular Function; Left; Cardiovascular Agents; Exercise Tolerance; Heart Failure; Stroke Volume; Urea; Ventricular Dysfunction; Left
Elenco autori:
Lewis, Gregory D; Voors, Adriaan A; Cohen-Solal, Alain; Metra, Marco; Whellan, David J; Ezekowitz, Justin A; Böhm, Michael; Teerlink, John R; Docherty, Kieran F; Lopes, Renato D; Divanji, Punag H; Heitner, Stephen B; Kupfer, Stuart; Malik, Fady I; Meng, Lisa; Wohltman, Amy; Felker, G Michael
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