Treatment with 24 hour istaroxime infusion in patients hospitalised for acute heart failure: a randomised, placebo-controlled trial
Articolo
Data di Pubblicazione:
2020
Citazione:
Treatment with 24 hour istaroxime infusion in patients hospitalised for acute heart failure: a randomised, placebo-controlled trial / Carubelli, Valentina; Zhang, Yuhui; Metra, Marco; Lombardi, Carlo; Felker, G Michael; Filippatos, Gerasimos; O'Connor, Christopher M; Teerlink, John R; Simmons, Phillip; Segal, Robert; Malfatto, Gabriella; La Rovere, Maria Teresa; Li, Dianfu; Han, Xiumin; Yuan, Zuyi; Yao, Yali; Li, Benjamin; Lau, Lit Fui; Bianchi, Giuseppe; Zhang, Jian. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1879-0844. - (2020). [10.1002/ejhf.1743]
Abstract:
Istaroxime is a first-in-class agent which acts through inhibition of the sarcolemmal Na+ /K+ pump and activation of the SERCA2a pump. This study assessed the effects of a 24 h infusion of istaroxime in patients hospitalised for acute heart failure (AHF).
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Acute heart failure; Istaroxime; Outcomes; SERCA2a; Therapy
Elenco autori:
Carubelli, Valentina; Zhang, Yuhui; Metra, Marco; Lombardi, Carlo; Felker, G Michael; Filippatos, Gerasimos; O'Connor, Christopher M; Teerlink, John R; Simmons, Phillip; Segal, Robert; Malfatto, Gabriella; La Rovere, Maria Teresa; Li, Dianfu; Han, Xiumin; Yuan, Zuyi; Yao, Yali; Li, Benjamin; Lau, Lit Fui; Bianchi, Giuseppe; Zhang, Jian
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