Data di Pubblicazione:
2016
Citazione:
Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial design / Bartunek, Jozef; Davison, Beth; Sherman, Warren; Povsic, Thomas; Henry, Timothy D; Gersh, Bernard; Metra, Marco; Filippatos, Gerasimos; Hajjar, Roger; Behfar, Atta; Homsy, Christian; Cotter, Gad; Wijns, William; Tendera, Michal; Terzic, Andre. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1388-9842. - 18:2(2016), pp. 160-168. [10.1002/ejhf.434]
Abstract:
Cardiopoiesis is a conditioning programme that aims to upgrade the cardioregenerative aptitude of patient-derived stem cells through lineage specification. Cardiopoietic stem cells tested initially for feasibility and safety exhibited signs of clinical benefit in patients with ischaemic heart failure (HF) warranting definitive evaluation. Accordingly, CHART-1 is designed as a large randomized, sham-controlled multicentre study aimed to validate cardiopoietic stem cell therapy.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Cardiopoiesis; Heart failure; Ischaemic cardiomyopathy; Regenerative medicine; Stem cell
Elenco autori:
Bartunek, Jozef; Davison, Beth; Sherman, Warren; Povsic, Thomas; Henry, Timothy D; Gersh, Bernard; Metra, Marco; Filippatos, Gerasimos; Hajjar, Roger; Behfar, Atta; Homsy, Christian; Cotter, Gad; Wijns, William; Tendera, Michal; Terzic, Andre
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