Generalized pseudoxanthoma elasticum with deficiency of vitamin K-dependent clotting factors

A patient with generalized cutis laxa-like pseudoxanthoma elasticum was found to have a congenital deficiency of vitamin K-dependent coagulation factors II, VII, IX, and X. This association may not be fortuitous and may define a particular subset of pseudoxanthoma elasticum with an autosomal recessive inheritance and the clinical features of generalized cutis laxa. © 1989, American Academy of Dermatology, Inc.. All rights reserved.