In vivo 2-Hydroxyglutarate Monitoring With Edited MR Spectroscopy for the Follow-up of IDH-Mutant Diffuse Gliomas: The IDASPE Prospective Study
Academic Article
Publication Date:
2023
Short description:
In vivo 2-Hydroxyglutarate Monitoring With Edited MR Spectroscopy for the Follow-up of IDH-Mutant Diffuse Gliomas: The IDASPE Prospective Study / Di Stefano, A.L., Nichelli, L., Berzero, G., Valabregue, R., Touat, M., Capelle, L., Pontoizeau, C., Bielle, F., Lerond, J., Giry, M., Villa, C., Baussart, B., Dehais, C., Galanaud, D., Baldini, C., Savatovsky, J., Dhermain, F., Deelchand, D.K., Ottolenghi, C., Lehericy, S., et al.. - In: NEUROLOGY. - ISSN 0028-3878. - 100:1(2023), pp. E94-E106. [Epub ahead of print] [10.1212/WNL.0000000000201137]
abstract:
D-2-hydroxyglutarate (2HG) characterizes IDH-mutant gliomas and can be detected and quantified with edited MRS (MEGA-PRESS). Here, we investigated the clinical, radiological, and molecular parameters affecting 2HG levels.
Iris type:
1.1 Articolo in rivista
Keywords:
2-hydroxyglutarate (2HG); IDH1/2 mutations; diffuse gliomas; edited MR spectroscopy; noninvasive detection
List of contributors:
Di Stefano, Anna Luisa; Nichelli, Lucia; Berzero, Giulia; Valabregue, Romain; Touat, Mehdi; Capelle, Laurent; Pontoizeau, Clément; Bielle, Franck; Lerond, Julie; Giry, Marine; Villa, Chiara; Baussart, Bertrand; Dehais, Caroline; Galanaud, Damien; Baldini, Capucine; Savatovsky, Julien; Dhermain, Frédéric; Deelchand, Dinesh K; Ottolenghi, Chris; Lehericy, Stephane; Marjańska, Małgorzata; Branzoli, Francesca; Sanson, Marc
Published in: