Data di Pubblicazione:
2010
Citazione:
Epstein-Barr virus-associated gastric carcinoma 33 years after kidney transplantation / Lunardi, Francesca; Calabrese, Fiorella; Furian, Lucrezia; Rigotti, Paolo; Valente, Marialuisa. - In: NDT PLUS. - ISSN 1753-0784. - 4:(2010), pp. 49-52. [10.1093/ndtplus/sfq197]
Abstract:
Epstein–Barr virus-associated gastric carcinoma (EBVaGC)
is a unique type of gastric cancer, defined as the presence
of EBV in gastric tumour cells, usually identified by
in situ hybridization. A poorly differentiated gastric adenocarcinoma
was detected in a kidney recipient 33 years after
transplantation. Neoplastic epithelial cells were EBV positive
by in situ hybridization. Gene sequencing confirmed
the amplicon specificity, and real-time polymerase chain
reaction quantified 2 600 000 genomes/μL DNA in neoplastic
tissue. No cases of EBVaGC have been reported
in solid organ transplants, thus this is the first case of
de novo EBVaGC arising in a 65-year-old renal transplant
recipient.
is a unique type of gastric cancer, defined as the presence
of EBV in gastric tumour cells, usually identified by
in situ hybridization. A poorly differentiated gastric adenocarcinoma
was detected in a kidney recipient 33 years after
transplantation. Neoplastic epithelial cells were EBV positive
by in situ hybridization. Gene sequencing confirmed
the amplicon specificity, and real-time polymerase chain
reaction quantified 2 600 000 genomes/μL DNA in neoplastic
tissue. No cases of EBVaGC have been reported
in solid organ transplants, thus this is the first case of
de novo EBVaGC arising in a 65-year-old renal transplant
recipient.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
trapianto di rene
Elenco autori:
Lunardi, Francesca; Calabrese, Fiorella; Furian, Lucrezia; Rigotti, Paolo; Valente, Marialuisa
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