Coexistence of multiple and widespread cardiovascular complications in a patient with Marfan syndrome

Inherited connective tissue diseases such as Marfan syndrome are frequently
associated with cardiovascular manifestations. Aortic involvement with dilation
and dissection is the most common finding and the major cause of death in Marfan
syndrome patients. We report the echocardiographic study of a 53-year-old male
patient with uncommon coexistence of cardiovascular abnormalities typical of
connective tissue disease at first clinical presentation in acute clinical
setting: dissection of the descending aorta associated with severe mitral
regurgitation due to leaflet flail and massive aortic insufficiency due to
ascending aortic enlargement, leading to left ventricular dilation and
dysfunction.