Breast cancer pathology

In recent years, the role of pathology in breast cancer has changed dramatically. Currently, it no longer has a purely diagnostic role, based exclusively on morphology. Pathologists are now asked to provide some information about prognostic and predictive factors, in other words about the risk assessment and the choice of the best treatment, according to Veronesi’s paradigm: “from maximum tolerable treatment to minimum effective treatment”. These changes can be summarized in this way: In the past we were dealing with “what to treat”, now we are dealing with “how to treat”, aiming at dealing with “whom to treat”.