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Insufficient reduction in heart rate during hospitalization despite beta-blocker treatment in acute decompensated heart failure: insights from the ASCEND-HF trial

Academic Article
Publication Date:
2016
Short description:
Insufficient reduction in heart rate during hospitalization despite beta-blocker treatment in acute decompensated heart failure: insights from the ASCEND-HF trial / Kitai, Takeshi; Grodin, Justin L; Mentz, Robert J; Hernandez, Adrian F; Butler, Javed; Metra, Marco; Mcmurray, John J; Armstrong, Paul W; Starling, Randall C; O'Connor, Christopher M; Swedberg, Karl; Tang, W H Wilson. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1388-9842. - (2016). [10.1002/ejhf.629]
abstract:
Heart failure (HF) can be associated with a higher resting heart rate (HR), and an elevated HR is associated with adverse long-term events. However, the mechanistic and causal role of HR in HF is unclear. This study aimed to investigate changes in HR during hospitalization, and the association between discharge HR and clinical outcomes as well as an interaction with beta-blocker therapy in patients with acute decompensated HF (ADHF).
Iris type:
1.1 Articolo in rivista
Keywords:
Beta-blocker; Heart failure; Heart rate; Heart rate reduction; Ivabradine
List of contributors:
Kitai, Takeshi; Grodin, Justin L; Mentz, Robert J; Hernandez, Adrian F; Butler, Javed; Metra, Marco; Mcmurray, John J; Armstrong, Paul W; Starling, Randall C; O'Connor, Christopher M; Swedberg, Karl; Tang, W H Wilson
Authors of the University:
METRA MARCO
Handle:
https://iris.unisr.it/handle/20.500.11768/193104
Published in:
EUROPEAN JOURNAL OF HEART FAILURE
Journal
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