Genetic and Pathological Characteristics of Frontotemporal Dementia with Right Anterior Temporal Predominance: A Multicenter Retrospective Cohort Study
Abstract
Data di Pubblicazione:
2025
Citazione:
Genetic and Pathological Characteristics of Frontotemporal Dementia with Right Anterior Temporal Predominance: A Multicenter Retrospective Cohort Study / Ulugut, H; Younes, K; Bertoux, M; Montembeault, M; Fumagalli, Gg; Ghirelli, A; Spinelli, Eg; Jung, Ny; Samancı, B; Illán-Gala, I; Thompson, J; Kobylecki, C; Santillo, A; Englund, E; Landqvist Waldö, M; Riedl, L; Van Den Stock, J; Vandenbulcke, M; Vandenberghe, R; Laforce, Jr. R.; Ducharme, S; Pressman, Ps; Tartaglia, C; Caramelli, P; Cruz De Souza, L; Tadao Takada, L; Morin, A; Schroeter, Ml; Kim, Ej; Young Moon, S; Agosta, F; Canu, E; Filippi, M; Gurvit, H; Diehl-Schmid, J; Galimberti, D; Lebouvier, T; Miller, Bl; Sturm, Ve; Miyagawa, T; Whitwell, Jl; Boeve, Bf; Rohrer, Jd; Gorno Tempini, Ml; Josephs, Ka; Snowden, Js; Warren, Jd; Rankin, Kp; Pijnenburg, Yal. - In: ALZHEIMER'S & DEMENTIA. - ISSN 1552-5260. - 21:Suppl 3(2025). [10.1002/alz70857_103987]
Abstract:
Background: Frontotemporal dementia (FTD) with right anterior temporal lobe (RATL) predominant atrophy is an emerging area of interest. Recent findings by the International Working Group (IWG) have identified this subtype as having a distinct clinical profile within the FTD spectrum (Ulugut et al., 2024, A&D). However, its genetic and pathological underpinnings remain unexplored in large, multicultural cohorts. Methods: Retrospective analyses encompassing clinical, genetic, pathological, and neuroimaging data from 23 IWG sites across 13 countries in Asia, Middle East, Europe, North and South America were conducted. The study included 444 patients with FTD exhibiting predominant RATL atrophy.
Tipologia CRIS:
1.5 Abstract in rivista
Elenco autori:
Ulugut, H; Younes, K; Bertoux, M; Montembeault, M; Fumagalli, Gg; Ghirelli, A; Spinelli, Eg; Jung, Ny; Samancı, B; Illán-Gala, I; Thompson, J; Kobylecki, C; Santillo, A; Englund, E; Landqvist Waldö, M; Riedl, L; Van Den Stock, J; Vandenbulcke, M; Vandenberghe, R; Laforce, Jr. R.; Ducharme, S; Pressman, Ps; Tartaglia, C; Caramelli, P; Cruz De Souza, L; Tadao Takada, L; Morin, A; Schroeter, Ml; Kim, Ej; Young Moon, S; Agosta, F; Canu, E; Filippi, M; Gurvit, H; Diehl-Schmid, J; Galimberti, D; Lebouvier, T; Miller, Bl; Sturm, Ve; Miyagawa, T; Whitwell, Jl; Boeve, Bf; Rohrer, Jd; Gorno Tempini, Ml; Josephs, Ka; Snowden, Js; Warren, Jd; Rankin, Kp; Pijnenburg, Yal
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