Bladder Preservation After Neoadjuvant Therapy for Muscle-invasive Bladder Cancer in the Current Era: Myth and Reality

: Bladder preservation after neoadjuvant therapy for muscle-invasive bladder cancer remains investigational. While randomized validation is awaited, growing prospective data, consensus standardization, and biomarker-driven strategies are transforming bladder-sparing strategies from an empirical alternative into a disciplined, evidence-maturing paradigm towards bladder-intact cure.