Open repair of descending thoracic aneurysms

with surgical graft replacement or endovascular exclusion. To reduce mortality and morbidity of open repair, a
multimodal approach has gradually evolved by maximizing organ protection.
Methods: On a total of 1108 patients treated in our Center from 1993 for pathology involving the thoracic
aorta, we reviewed the prospectively collected data of 194 consecutive patients who underwent open thoracic
aortic aneurysm repair, 104 (54%) for degenerative aneurysms, 65 (34%) for dissections, 25 (12%) for other
pattern of disease. Left Heart Bypass was used in 82% of cases, clamp and sew technique in 16%, hypotermic
circulatory arrest in 2%.
Results: Overall perioperative mortality was 4.1%. The rate of pulmonary complications was 8.8%. The rate
of cardiac complications, i.e. new onset myocardial necrosis demonstrated by positive blood tests, was 6.2%.
The rate of renal complications was 7.2%. Cerebrovascular accident, defined as a new neurologic deficit lasting
more than 24 hours confirmed by imaging, occurred in 2.0% of patients. The rate of spinal cord ischemia,
manifesting either as paraplegia or paraparesis, was 4.6%.
Conclusions: Mortality and morbidity rates of open thoracic aortic aneurysm repair are currently satisfactory
especially in fit patients. In order to define surgical indications and the role of endovascular repair, consideration
of age of the patient, comorbidity, symptoms, life expectancy, likely quality of life (if asymptomatic),
aortic diameter, aneurysm morphology, aneurysm extent, suitability of landing zones, and operator experience
are all distinctly relevant.