Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus
Articolo
Data di Pubblicazione:
2016
Citazione:
Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus / Conteduca, Vincenza; Santoni, Matteo; Medri, Matelda; Scarpi, Emanuela; Burattini, Luciano; Lolli, Cristian; Rossi, Lorena; Savini, Agnese; Berardi, Rossana; Stanganelli, Ignazio; Cascinu, Stefano; De Giorgi, Ugo. - In: CLINICAL GENITOURINARY CANCER. - ISSN 1558-7673. - 100:(2016), pp. 99-106. [10.1016/j.clgc.2016.02.012]
Abstract:
In clinical practice, discontinuation or dose reduction of everolimus may be induced not only by grade 3 or 4 toxicities but also by prolonged grade 2 toxicities, such as stomatitis and/or cutaneous toxicity, which share some pathogenetic mechanisms. We assessed the correlation between either everolimus discontinuation or dose reduction induced by stomatitis-cutaneous toxicity events (SCTE) and clinical outcome of patients with metastatic renal-cell cancer (mRCC).
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Dose reduction; Metastatic renal-cell cancer; Predictive marker; Skin toxicities; Survival
Elenco autori:
Conteduca, Vincenza; Santoni, Matteo; Medri, Matelda; Scarpi, Emanuela; Burattini, Luciano; Lolli, Cristian; Rossi, Lorena; Savini, Agnese; Berardi, Rossana; Stanganelli, Ignazio; Cascinu, Stefano; De Giorgi, Ugo
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