One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery
Articolo
Data di Pubblicazione:
2020
Abstract:
The Perioperative Ischemic Evaluation-2 study (POISE-2) authors previously reported that neither aspirin nor clonidine reduced a 30-day composite of nonfatal myocardial infarction or death. Aspirin caused perioperative bleeding, and clonidine provoked hypotension and bradycardia.In a subgroup analysis of patients who had previous percutaneous coronary interventions, those given aspirin had fewer infarctions or deaths.
Tipologia CRIS:
1.1 Articolo in rivista
Elenco autori:
Sessler, Daniel I; Conen, David; Leslie, Kate; Yusuf, Salim; Popova, Ekaterina; Graham, Michelle; Kurz, Andrea; Villar, Juan Carlos; Mrkobrada, Marko; Sigamani, Alben; Biccard, Bruce M; Meyhoff, Christian S; Parlow, Joel L; Guyatt, Gordon; Xavier, Denis; Chan, Matthew T V; Kumar, Priya A; Forget, Patrice; Malaga, German; Fleischmann, Edith; Amir, Mohammed; Torres, David; Wang, C Y; Paniagua, Pilar; Berwanger, Otavio; Srinathan, Sadeesh; Landoni, Giovanni; Manach, Yannick Le; Whitlock, Richard; Lamy, André; Balasubramanian, Kumar; Gilron, Ian; Turan, Alparslan; Pettit, Shirley; Devereaux, P J
Link alla scheda completa:
Pubblicato in: