Comprehensive Assessment of Immuno-oncology Biomarkers in Adenocarcinoma, Urothelial Carcinoma, and Squamous-cell Carcinoma of the Bladder
Articolo
Data di Pubblicazione:
2020
Abstract:
A retrospective analysis of genomic alterations in pure bladder adenocarcinoma and pure squamous-cell carcinoma, compared with the classical urothelial carcinoma, revealed similar opportunities for immunotherapy between urothelial carcinoma and squamous-cell tumors, whereas adenocarcinoma cases expressed immunotherapy biomarkers less frequently. The landscape of genomic alterations between these rare histologies was different.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Bladder adenocarcinoma; Bladder squamous-cell carcinoma; Genomic alterations; Immunotherapy biomarkers; Variant histologies
Elenco autori:
Necchi, A.; Madison, R.; Raggi, D.; Jacob, J. M.; Bratslavsky, G.; Shapiro, O.; Elvin, J. A.; Vergilio, J. -A.; Killian, J. K.; Ngo, N.; Ramkissoon, S.; Severson, E.; Hemmerich, A. C.; Huang, R.; Ali, S. M.; Chung, J. H.; Reddy, P.; Miller, V. A.; Schrock, A. B.; Gay, L. M.; Alexander, B. M.; Grivas, P.; Ross, J. S.
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