Publication Date:
2012
Short description:
Polyclonal serum-free light chains elevation in HIV-infected patients / Bibas, M., Lorenzini, P., Cozzi-Lepri, A., Calcagno, A., Di Giambenedetto, S., Costantini, A., Castagna, A., Manfrin, V., Monforte, A.D., Antinori, A.. - In: AIDS. - ISSN 0269-9370. - 26:16(2012), pp. 2107-2110. [10.1097/QAD.0b013e328358d54b]
abstract:
We investigated the association between polyclonal serum-free light chains and prognostic biomarkers routinely used in the setting of HIV infection. For this purpose serum samples of 182 HIV-infected patients from the Italian Cohort of Antiretroviral Naive Patients foundation cohort were analysed. We found that polyclonal serum free light chains above the upper normal limit are strongly correlated in HIV-infected patients with advancing age, shorter time of undetectable HIV viremia, higher viral load and with lower CD4 cell count at sample. Copyright © 2012 Lippincott Williams &Wilkins.
Iris type:
1.1 Articolo in rivista
Keywords:
Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Biomarkers; CD4 Lymphocyte Count; Female; Humans; Immunoglobulin kappa-Chains; Immunoglobulin lambda-Chains; Immunologic Factors; Male; Middle Aged; RNA, Viral; Viral Load
List of contributors:
Bibas, M.; Lorenzini, P.; Cozzi-Lepri, A.; Calcagno, A.; Di Giambenedetto, S.; Costantini, A.; Castagna, A.; Manfrin, V.; Monforte, A. D.; Antinori, A.
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