Development and in-vivo Assessment of a Novel MRI-Compatible Headframe System for the Ovine Animal Model

The brain of sheep has primarily been used in neuroscience as an animal model because of its similarity to the human brain, in particular if compared to other models such as the lissencephalic rodent brain. Their brain size also makes sheep an ideal model for the development of neurosurgical techniques using conventional clinical CT/MRI scanners, and stereotactic systems for neurosurgery.