Data di Pubblicazione:
2022
Abstract:
Objective: Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar inso-lation at the onset location was associated with the polarity of the first episode of BD I. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area of the Earth. Methods: Data from 7488 patients with BD I were collected at 75 sites in 42 countries. The first episode occurred at 591 onset locations in 67 countries at a wide range of latitudes in both hemispheres. Solar insolation values were obtained for every onset location, and the ratio of the minimum mean monthly insolation to the maximum mean monthly insolation was calculated. This ratio is largest near the equator (with little change in solar insolation over the year), and smallest near the poles (where winter insolation is very small compared to summer insolation). This ratio also applies to tropical locations which may have a cloudy wet and clear dry season, rather than winter and summer. Results: The larger the change in solar insolation throughout the year (smaller the ratio between the minimum monthly and maximum monthly values), the greater the likelihood the first episode polarity was depression. Other associated variables were being female and increasing percentage of gross domestic product spent on country health expenditures. (All coefficients: P <= 0.001). Conclusion: Increased awareness and research into circadian dysfunction throughout the course of BD is warranted.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Bipolar disorder; Circadian rhythm; Depression; Polarity; Solar insolation; Sunlight; Circadian Rhythm; Female; Humans; Male; Seasons; Sunlight; Bipolar Disorder
Elenco autori:
Bauer, Michael; Glenn, Tasha; Achtyes, Eric D; Alda, Martin; Agaoglu, Esen; Altınbaş, Kürşat; Andreassen, Ole A; Angelopoulos, Elias; Ardau, Raffaella; Aydin, Memduha; Ayhan, Yavuz; Baethge, Christopher; Bauer, Rita; Baune, Bernhard T; Balaban, Ceylan; Becerra-Palars, Claudia; Behere, Aniruddh P; Behere, Prakash B; Belete, Habte; Belete, Tilahun; Belizario, Gabriel Okawa; Bellivier, Frank; Belmaker, Robert H; Benedetti, Francesco; Berk, Michael; Bersudsky, Yuly; Bicakci, Şule; Birabwa-Oketcho, Harriet; Bjella, Thomas D; Brady, Conan; Cabrera, Jorge; Cappucciati, Marco; Castro, Angela Marianne Paredes; Chen, Wei-Ling; Cheung, Eric Y W; Chiesa, Silvia; Crowe, Marie; Cuomo, Alessandro; Dallaspezia, Sara; Del Zompo, Maria; Desai, Pratikkumar; Dodd, Seetal; Etain, Bruno; Fagiolini, Andrea; Fellendorf, Frederike T; Ferensztajn-Rochowiak, Ewa; Fiedorowicz, Jess G; Fountoulakis, Kostas N; Frye, Mark A; Geoffroy, Pierre A; Gonzalez-Pinto, Ana; Gottlieb, John F; Grof, Paul; Haarman, Bartholomeus C M; Harima, Hirohiko; Hasse-Sousa, Mathias; Henry, Chantal; Høffding, Lone; Houenou, Josselin; Imbesi, Massimiliano; Isometsä, Erkki T; Ivkovic, Maja; Janno, Sven; Johnsen, Simon; Kapczinski, Flávio; Karakatsoulis, Gregory N; Kardell, Mathias; Kessing, Lars Vedel; Kim, Seong Jae; König, Barbara; Kot, Timur L; Koval, Michael; Kunz, Mauricio; Lafer, Beny; Landén, Mikael; Larsen, Erik R; Lenger, Melanie; Lewitzka, Ute; Licht, Rasmus W; Lopez-Jaramillo, Carlos; Mackenzie, Alan; Madsen, Helle Østergaard; Madsen, Simone Alberte Kongstad A; Mahadevan, Jayant; Mahardika, Agustine; Manchia, Mirko; Marsh, Wendy; Martinez-Cengotitabengoa, Monica; Martiny, Klaus; Mashima, Yuki; Mcloughlin, Declan M; Meesters, Ybe; Melle, Ingrid; Meza-Urzúa, Fátima; Mok, Yee Ming; Monteith, Scott; Moorthy, Muthukumaran; Morken, Gunnar; Mosca, Enrica; Mozzhegorov, Anton A; Munoz, Rodrigo; Mythri, Starlin V; Nacef, Fethi; Nadella, Ravi K; Nakanotani, Takako; Nielsen, René Ernst; O'Donovan, Claire; Omrani, Adel; Osher, Yamima; Ouali, Uta; Pantovic-Stefanovic, Maja; Pariwatcharakul, Pornjira; Petite, Joanne; Pfennig, Andrea; Ruiz, Yolanda Pica; Pinna, Marco; Pompili, Maurizio; Porter, Richard; Quiroz, Danilo; Rabelo-da-Ponte, Francisco Diego; Ramesar, Raj; Rasgon, Natalie; Ratta-Apha, Woraphat; Ratzenhofer, Michaela; Redahan, Maria; Reddy, M S; Reif, Andreas; Reininghaus, Eva Z; Richards, Jenny Gringer; Ritter, Philipp; Rybakowski, Janusz K; Sathyaputri, Leela; Scippa, Ângela M; Simhandl, Christian; Smith, Daniel; Smith, José; Stackhouse, Paul W; Stein, Dan J; Stilwell, Kellen; Strejilevich, Sergio; Su, Kuan-Pin; Subramaniam, Mythily; Sulaiman, Ahmad Hatim; Suominen, Kirsi; Tanra, Andi J; Tatebayashi, Yoshitaka; Teh, Wen Lin; Tondo, Leonardo; Torrent, Carla; Tuinstra, Daniel; Uchida, Takahito; Vaaler, Arne E; Vieta, Eduard; Viswanath, Biju; Yoldi-Negrete, Maria; Yalcinkaya, Oguz Kaan; Young, Allan H; Zgueb, Yosra; Whybrow, Peter C
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