Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy
Articolo
Data di Pubblicazione:
2016
Citazione:
Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy / Perez, Antonio L; Grodin, Justin L; Wu, Yuping; Hernandez, Adrian F; Butler, Javed; Metra, Marco; Felker, G Michael; Voors, Adriaan A; Mcmurray, John J; Armstrong, Paul W; Starling, Randall C; O'Connor, Christopher M; Tang, W H Wilson. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1388-9842. - 18:3(2016), pp. 290-297. [10.1002/ejhf.456]
Abstract:
Endothelin-1 (ET-1) is an endogenous vasoconstrictor implicated in pulmonary and systemic hypertension, as well as ventricular dysfunction, through effects on vascular smooth muscle, the kidneys, and cardiomyocytes. We aimed to determine the association between serial ET-1 levels and acute heart failure patient outcomes.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Acute heart failure; Endothelin-1; Prognosis
Elenco autori:
Perez, Antonio L; Grodin, Justin L; Wu, Yuping; Hernandez, Adrian F; Butler, Javed; Metra, Marco; Felker, G Michael; Voors, Adriaan A; Mcmurray, John J; Armstrong, Paul W; Starling, Randall C; O'Connor, Christopher M; Tang, W H Wilson
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