Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF)
Articolo
Data di Pubblicazione:
2018
Citazione:
Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF) / Suzuki, Toru; Yazaki, Yoshiyuki; Voors, Adriaan A; Jones, Donald J L; Chan, Daniel C S; Anker, Stefan D; Cleland, John G; Dickstein, Kenneth; Filippatos, Gerasimos; Hillege, Hans L; Lang, Chim C; Ponikowski, Piotr; Samani, Nilesh J; Van Veldhuisen, Dirk J; Zannad, Faiez; Zwinderman, Aeilko H; Metra, Marco; Ng, Leong L. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1879-0844. - (2018). [10.1002/ejhf.1338]
Abstract:
Association of elevated circulating levels of trimethylamine N-oxide (TMAO) with adverse outcomes in patients with heart failure (HF) has been described. However, response of TMAO levels to treatment and medications has not been investigated. Therefore, we investigated whether TMAO levels are responsive to guideline-recommended treatment and medications, and further reflect changes in outcomes.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Biomarker; Gut microbiome; Heart failure; Metabolite; Outcome study
Elenco autori:
Suzuki, Toru; Yazaki, Yoshiyuki; Voors, Adriaan A; Jones, Donald J L; Chan, Daniel C S; Anker, Stefan D; Cleland, John G; Dickstein, Kenneth; Filippatos, Gerasimos; Hillege, Hans L; Lang, Chim C; Ponikowski, Piotr; Samani, Nilesh J; Van Veldhuisen, Dirk J; Zannad, Faiez; Zwinderman, Aeilko H; Metra, Marco; Ng, Leong L
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