Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF)
Academic Article
Publication Date:
2018
Short description:
Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF) / Suzuki, Toru; Yazaki, Yoshiyuki; Voors, Adriaan A; Jones, Donald J L; Chan, Daniel C S; Anker, Stefan D; Cleland, John G; Dickstein, Kenneth; Filippatos, Gerasimos; Hillege, Hans L; Lang, Chim C; Ponikowski, Piotr; Samani, Nilesh J; Van Veldhuisen, Dirk J; Zannad, Faiez; Zwinderman, Aeilko H; Metra, Marco; Ng, Leong L. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1879-0844. - (2018). [10.1002/ejhf.1338]
abstract:
Association of elevated circulating levels of trimethylamine N-oxide (TMAO) with adverse outcomes in patients with heart failure (HF) has been described. However, response of TMAO levels to treatment and medications has not been investigated. Therefore, we investigated whether TMAO levels are responsive to guideline-recommended treatment and medications, and further reflect changes in outcomes.
Iris type:
1.1 Articolo in rivista
Keywords:
Biomarker; Gut microbiome; Heart failure; Metabolite; Outcome study
List of contributors:
Suzuki, Toru; Yazaki, Yoshiyuki; Voors, Adriaan A; Jones, Donald J L; Chan, Daniel C S; Anker, Stefan D; Cleland, John G; Dickstein, Kenneth; Filippatos, Gerasimos; Hillege, Hans L; Lang, Chim C; Ponikowski, Piotr; Samani, Nilesh J; Van Veldhuisen, Dirk J; Zannad, Faiez; Zwinderman, Aeilko H; Metra, Marco; Ng, Leong L
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