Incidence of malignancies in HIVinfected patients and prognostic role of current CD4 cell count: evidence from a large Italian cohort study
Academic Article
Publication Date:
2010
Short description:
Incidence of malignancies in HIVinfected patients and prognostic role of current CD4 cell count: evidence from a large Italian cohort study / Prosperi, M. C. F.; Cozzi lepri, A.; Castagna, Antonella; Mussini, C.; Murri, R.; Giacometti, A.; Torti, C.; Costantini, A.; Narciso, P.; Ghinelli, F.; Antinori, A.; D'arminio Monforte, A.. - In: CLINICAL INFECTIOUS DISEASES. - ISSN 1058-4838. - 50:9(2010), pp. 1316-1321. [10.1086/651688]
abstract:
The incidence of and predictors of acquired immunodeficiency syndrome-defining malignancies (ADMs) and nonADM (NADMs) were evaluated in a large Italian cohort. The incidence of ADM and NADM was 5.0 cases per 1000 personyears of follow-up (95% confidence interval, 4.3-5.8 cases per 1000 person-years of follow-up) and 2.4 cases per 1000 person-years of follow-up (95% confidence interval, 1.9-3.1 cases per 1000 person-years of follow-up), respectively. Lower current CD4 cell count was an independent predictor of developing malignancies, with the association being stronger for ADM than for NADM. © 2010 by the Infectious Diseases Society of America. All rights reserved.
Iris type:
1.1 Articolo in rivista
Keywords:
Adult; CD4 Lymphocyte Count; Cohort Studies; Female; HIV Infections; Humans; Incidence; Italy; Male; Neoplasms; Prognosis; Microbiology (medical); Infectious Diseases
List of contributors:
Prosperi, M. C. F.; Cozzi lepri, A.; Castagna, Antonella; Mussini, C.; Murri, R.; Giacometti, A.; Torti, C.; Costantini, A.; Narciso, P.; Ghinelli, F.; Antinori, A.; D'arminio Monforte, A.
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